【摘要】 [目的]分析胃肠道间质瘤(gastrointestinal stromal tumors,GIST)的CT表现并探讨对肿瘤恶性的预测价值。[方法]回顾性分析和评估经病理组织学检查和免疫组化检测证实为胃的GIST患者64例的CT检查影像表现,依照以下CT参数进行了分析:病变位置、大小、形态、边缘、生长方式、静脉对比增强方式、增强强度、邻近器官的侵犯、溃疡、瘘管、钙化、肠系膜脂肪浸润、淋巴结肿大及远处转移的存在,并根据GIST生物学行为进行分级评估与CT表现之间的关系。[结果]肿瘤病变位置多位于胃体(P=0.024);较多表现为外生性生长46%;多表现为中度增强(P=0.000),较少出现邻近器官的侵犯、钙化、肠系膜脂肪浸润、淋巴结肿大及远处转移(均P<0.01);肿瘤大小与生长方式、增强方式均无统计学关联(P>0.05);各侵袭危险性GIST分组在肿瘤大小、形态、生长方式、强化方式、强化强度、肠系膜脂肪浸润、淋巴结肿大、钙化、周围侵犯、转移方面有统计学意义(P<0.05)。[结论]GIST具有特征性的CT影像学表现及临床特征,肿瘤的CT表现与生物学评价具有相关性,掌握其特征对于其诊断、治疗及预后评价具有重要意义。更多还原

【Abstract】 [Objective]To investigate and describe the CT findings of 64 cases with gastric stromal tumor and its predictive values on tumor malignancy.[Methods]Sixty four cases patients with histopathologically and immunohistochemically confirmed gastric stromal tumors,who had already been submitted to computed tomography scans before the treatment,were evaluated.The following tomographic variables were analyzed:lesion topography,size/dimensions,contour,morphology,pattern and intravenous contrastenhancement intensity,growth pattern,invasion of adjacent organs,fistula,calcifications,mesenteric fat infiltration,lymphadenomegaly and presence of distant metastasis.And according to biology behaviors of the GIST to evaluate the relationship between the CT performance.[Results]More cases Tumors were found in the body(P=0.024);Predominantly extraluminal growth was morelikely observed in these cases(46%).There were more cases indicated moderate intravenous contrast-enhancement intensity(P=0.000);invasion of adjacent organs,fistula,calcifications,mesenteric fat infiltration,lymphadenomegaly and presence of distant metastasis were infrequenty found in these cases(all P<0.01);there was no significant relations in size with growth pattern and pattern of intravenous contrast-enhancement(P>0.05).there was significant relations in lesion topography,size/dimensions,contour,morphology,pattern and intravenous contrast-enhancement intensity,growth pattern,invasion of adjacent organs,fistula,calcifications,mesenteric fat infiltration,lymphadenomegaly and presence of distant metastasis with the invasion risk group.[Conclusion]Gastric stromal tumors have characteristic CT imaging findings and clinical characteristics.CT manifesta-tions of tumor is associated with biological evaluation.Its characteristics are very important for diagnosis and treatment and prognosis evaluation of the tumor.更多还原