【摘要】 目的采用磁共振轴位测量布-加综合征(BCS)患者的肝尾状叶横径,并研究其临床意义。方法搜集本院2015年6月至2016年1月经临床、实验室及影像学检查证实的BCS患者55例(BCS组)、乙型病毒性肝炎后肝硬化患者30例(乙肝肝硬化组)以及正常对照者31名(正常对照组),行磁共振检查。测量轴位尾状叶横径、肝右叶横径并计算二者比值,统计学方法对照研究三组各指标的差异。绘制受试者工作特征曲线(ROC),并计算曲线下面积(AUC)。结果 BCS组尾状叶横径(57.23±15.22)mm,较正常对照组、乙肝肝硬化组增大(P<0.01)。BCS组尾状叶横径与肝右叶横径比值0.57±0.15,较正常对照组、乙肝肝硬化组增大(P<0.01)。绘制BCS组对正常对照组的ROC曲线,尾状叶横径AUC为0.916,尾状叶与肝右叶横径比值AUC为0.909。当尾状叶横径切割点值为42.24 mm时,敏感度为85.8%,特异度为87.1%。当尾状叶与肝右叶横径比值切割点值为0.432时,敏感度为83.6%,特异度为83.9%。结论轴位测量肝尾状叶横径、尾状叶横径与肝右叶横径比值有助于诊断BCS。更多还原

【Abstract】 Objective To investigate the transverse diameter of caudate lobe,transverse diameter of right hepatic lobe and ratio of the two in patients with Budd-Chiari syndrome( BCS) and its clinical diagnostic significance. Methods From Jun. 2015 to Jan. 2016,55 BCS patients and 30 patients with cirrhosis due to hepatitis B virus( HBV) underwent clinical,laboratory and imaging examination as well as 31 control individuals were included,and all individuals received MRI examination. The transverse diameters of caudate lobe and right hepatic lobe and ratio of the two were measured for control study of various indicators in all three groups. The receiver operating characteristic curve( ROC) was drawn,and the area under the curve( AUC) was calculated. Results The transverse diameter of the caudate lobe in patients with BCS( 57. 23 ± 15. 22) mm was significantly higher than patients with cirrhosis due to hepatitis B virus( HBV) and normal adults( Both P < 0. 01). The ratio of two transverse diameters in patients with BCS( 0. 57 ± 0. 15) was significantly higher than patients with cirrhosis due to hepatitis B virus( HBV) and normal adults( Both P < 0. 01). AUC( transverse diameter of caudate lobe) of ROC was 0. 916,AUC( The ratio of two transverse diameters) of ROC was 0. 909. When the cutoff value of transverse diameter of the caudate lobe was set at 42. 24 mm,the sensitivity and specificity were 85. 8 ﹪ and 87. 1 ﹪respectively. When the cutoff value of the ratio of the two transverse diameters was set at 0. 432,the sensitivity and specificity was 83. 6 ﹪ and 83. 9 ﹪ respectively. Conclusion The levels of the transverse diameter of caudate lobe and the ratio of the two transverse diameters are important in the diagnosis of BCS.更多还原