【摘要】 目的探讨哮喘患儿外周血白皙白介素2、白细胞介素4、嗜酸粒细胞水平变化特点。方法方便选取该院2015年11月—2016年11月期间收治80例哮喘患儿作为研究组;另选取同期(2015年11月—2016年11月期间)于该院体检的40名健康儿童作为对照组。研究组哮喘患儿、对照组健康儿童均接受外周血IL-2、IL-4、EOS检验,分别对比研究组哮喘患儿、对照组健康儿童以及危重组哮喘患儿、普通组哮喘患儿上述指标检测结果。结果研究组IL-4(32.52±6.54)pg/L、EOS(10.54±2.11)%检测结果显著高于对照组[IL-4(6.05±1.03)pg/L、EOS(1.41±0.96)%],而该组IL-2(15.69±2.08)pg/L检测结果则显著低于对照组IL-2(24.98±4.65)pg/L(P<0.05);研究组哮喘儿童中,危重组患儿IL-4(49.26±11.23)pg/L、EOS(17.43±3.55)%检测结果显著高于普通组[IL-4(26.33±3.38)pg/L、EOS(5.61±1.30)%],而其IL-2(12.36±1.27)pg/L检测结果则显著低于普通组IL-2(17.84±2.91)pg/L(P<0.05)。结论临床医生应准确掌握哮喘患儿机体外周血IL-2、IL-4、EOS检测特点,接诊病例后积极给予各项检查确诊病情,根据其实际情况提供针对性的治疗方案,有利于保障患儿生活质量及生命安全。更多还原

【Abstract】 Objective To study the change features of peripheral blood IL-2, IL-4, eosinophilic granulocyte levels in asthma children and clinical value. Methods Convenient selection 80 cases of asthma children admitted and treated in our hospital from November 2015 to November 2016 were selected as the research group, and 40 cases of healthy children at the same period were selected as the control group, and the both groups received the peripheral blood IL-2, IL-4, eosinophilic granulocyte examination, and the test results of the above indexes in the research group, control group, critical illness group and common group were analyzed and compared. Results The IL-4 and EOS test results in the research group were obviously higher than those in the control group,[(32.52±6.54)pg/L,(10.54±2.11)% vs IL-4(6.05±1.03)pg/L, 1.41±0.96)%], but the test result of IL-2 was obviously lower than that in the control group[(15.69±2.08)pg/L vs(24.98±4.65)pg/L](P<0.05),and the test result of IL-4 and EOS in the critical group were obviously higher than those in the common group [(49.26±11.23)pg/L,(17.43±3.55)% vs(26.33±3.38)pg/L,(5.61±1.30)%], and the test result of IL-2 was obviously lower than that in the common group,[(12.36±1.27)pg/L vs(17.84±2.91)pg/L](P<0.05). Conclusion The clinical doctors should accurately master the test features of organism peripheral blood of asthma children, and conduct various examinations as soon as possible in order to diagnose the diseases and provide the targeted treatment plan according to the practical conditions thus ensuring the quality of life and life security of children.更多还原