【摘要】 目的研究体积栓塞比(VER)对破裂颅内动脉瘤患者术后早期康复及后期动脉瘤再复发的意义。方法选取2015-01—2016-12间接收的破裂颅内动脉瘤患者60例,随机法分成研究组和对照组,对照组采用血管内栓塞法进行治疗,研究组在对照组基础上就患者进行VER测量并根据VER的值确定是否进一步栓塞。结果治疗后,研究组患者的患者意识障碍、颅内高压症状、神经功能障碍、脑积水缓解程度等症状缓解程度大于对照组患者,差异有统计学意义(P<0.05)。研究组患者在治疗后出现动脉瘤二次破裂、血管痉挛、脑缺血以及感染等并发症情况的例数明显少于对照组患者,差异有统计学意义(P<0.05)。研究组患者治疗后复发率为6.67%,对照组患者复发率为26.67%,研究组患者复发率明显少于对照组,差异有统计学意义(χ~2=4.3200,P=0.0377)。结论 VER是评价动脉瘤栓塞程度的客观指标,对于栓塞术后动脉瘤的复发和再出血具有一定的预测意义。更多还原

【Abstract】 Objective To study the effect of VER on the early recovery and postoperative recurrence of ruptured intracranial aneurysm. Methods 60 patients with ruptured intracranial aneurysms received in the hospital from January,2015 to December,2016 were randomly divided into study group and control group. The control group was treated by endovascular embolization. Control group received VER measurement based on control group,and further embolization was determined based on the value of VER. Results After treatment,the symptoms of patients with consciousness disturbance,intracranial hypertension,neurological dysfunction,hydrocephalus alleviation and other symptoms of the study group were significantly higher than those of the control group( P < 0. 05).The incidence of secondary rupture of aneurysm,vasospasm,cerebral ischemia and infection was significantly lower in the study group than in the control group( P < 0. 05). The relapse rate was 6. 67% in the study group and 26. 67% in the control group. The relapse rate in the study group was significantly lower than that in the control group( χ2= 4. 3200,P = 0. 0377). Conclusion VER is an objective index for assessing the degree of embolization of aneurysm,and it has a certain prognostic significance for the recurrence and rebleeding of aneurysm after embolization.更多还原