【摘要】 目的观察双微导管技术血管内栓塞治疗临床效果及对患者认知功能的影响。方法将80例颅内宽颈动脉瘤患者随机分为观察组和对照组各40例,观察组采用双微导管技术行血管内栓塞治疗,对照组采用自膨式支架(LEO支架)辅助结合弹簧圈栓塞治疗;对患者行为期1年的术后随访,观察患者临床疗效及术后并发症情况,并在术后1年时采用简易精神状态检查量表(Mini-Mental State Examinatlon,MMSE)评价患者认知功能。结果观察组总有效率为97.5%,明显高于对照组的77.5%(P<0.01);观察组MMSE计算及注意力、记忆力、定向力、语言能力及回忆力5个维度评分均明显高于对照组(P<0.01);观察组术后并发症总发生率为5.0%,对照组为15.0%,但差异无统计学意义(χ~2=1.250,P>0.05)。结论采用双微导管技术行血管内栓塞治疗,其临床效果显著,可改善患者术后认知功能异常,具有较高的临床应用价值。更多还原

【Abstract】 Objective To analyze the clinical efficacy of double micro catheter technique in patients with endovascular embolization and its effect on cognitive function of patients.Methods Eighty cases of intracranial wide necked aneurysms were divided into the observation group and the control group randomly,and each group had 40 cases.The observation group was treated with endovascular embolization through double micro catheter technique,while the control group was treated with self-expanding stent(LEO stent)and coil embolization.The patients were followed up for one year,and the clinical efficacy and postoperative complications were observed.The patient′s cognitive function was evaluated by the Mini-Mental State Examinatlon(MMSE)1 years after the operation.Results The total effective rate of the observation group was 97.5%,significantly higher than 77.5% of the control group(P<0.01).The MMSE score of the observation group and it′s 5 dimensions of attention,memory,orientation,language ability and memory ability were significantly higher than those in the control group(P<0.01).The total incidence of postoperative complications was 5% in the observation group and 15%in the control group,and the different was not significant(χ~2=1.250,P>0.05).Conclusion The clinical effect of double micro catheter technique for treating endovascular embolization is remarkable,and it can improve the postoperative cognitive dysfunction.It has higher clinical value.更多还原