【摘要】 目的:探讨超声检测对提高重型α-地中海贫血胎儿检出率的意义。方法:将2008年1月至2016年8月经确诊的70例孕期重型α-地中海贫血胎儿作为观察组,以同孕期的70例正常胎儿为对照组,比较两组胎儿的超声三尖瓣环收缩偏移(tricuspid annular plane systolic excursion,TAPSE)值。结果:观察组胎儿TAPSE值随着孕龄的增加较对照组胎儿TAPSE值增长速度慢,同期两组间TAPSE值差异有统计学意义(P<0.05)。结论:超声测定TAPSE值可作为评估重型α-地中海贫血胎儿的一项指标,能提高该病胎儿的检出率。更多还原

【Abstract】 Objective: To explore the significance of ultrasonography on improving the detection rate of severe α-thalassaemia fetus. Methods: 70 cases of severeα-thalassaemia fetus in our hospital from January 2008 to August 2016 were selected as research group,and 70 cases of normal fetus were in the control group. Tricuspid annular plane systolic excursion( TAPSE) values of patients were compared in the two groups. Results: TAPSE values increased with the increase of gestational age while the increased velocity of TAPSE values in the research group was slower than that in the control group,and the difference between the two groups was statistically significant( P < 0. 05). Conclusion: The TAPSE value by ultrasonography can be used as an indicator to assess the fetus of severe α-thalassaemia,and can improve the detection rate.更多还原