【摘要】 目的:分析我院辅助用药发生不良反应(adverse drug reaction,ADR)的特点,为临床合理用药提供参考。方法:对我院2014~2016年上报的药物不良反应报表中288例涉及辅助性用药引起的不良反应进行回顾性研究分析。结果:发现新的严重的ADR共13例(4.5%),ADR多发于50岁以上患者(61.46%),不良反应发生最多的给药途径为静脉滴注(94.44%),累及的系统主要为皮肤及其附件(29.55%)和心血管系统(21.37%),ADR发生率高的辅助用药情况为西医无经中医会诊使用中成药(21.88%)、氨基酸及营养制剂(17.01%)及改善心脑血管循环药物(12.85%)。结论:医院需进一步加强ADR监测,医生应重视辅助用药引起的ADR,同时药师要积极参与辅助用药合理用药点评,定期分析反馈,促进临床合理用药。更多还原

【Abstract】 Obiective:To analyze the characteristics and regularity of adverse drug reactions(ADR)of the adjuvant drugs in our hospital,and to provide reference for rational drug use in clinic.Methods:288 cases of adverse drug reactions reported refer to the adjuvant drugs in our hospital during 2014 ~2016 were analyzed retrospectively.Results:It was found that the total of new and serious ADR were 17cases(5.9%). ADR of adjuvant drugs mainly occurred in patients aged 50 years above(61.46%). Intravenous dripping was the main route of administration(94.44%). The organs or systems involved in ADR was the skin and its accessories(29.55%) and cardiovascular system(21.37%).The high rate of ADR in the adjuvant were use of traditional Chinese medicine without Traditional Chinese medicine diagnosis(21.88%), use of amino acid and nutrition preparations(17.01%) and use of improved cardiovascular and cerebrovascular circulation drugs(12.85%).for western medicine without doctors of traditional Chinese medicine with Chinese medicine(21.88%),(17.01%) and amino acid nutrition and improve cardiovascular circulation drugs(12.85%).Conclusion: Hospital should further strengthen ADR monitoring,doctors should pay attention to ADR caused by the adjuvant drugs,while pharmacists should actively participate in the rational use of drug reviews,regular analysis of feedback to promote clinical rational drug use.更多还原