【摘要】 目的:分析探讨中药制剂临床应用的不良反应(ARDs)原因并据此提出防范对策。方法:回顾性分析2013年5月—2015年10月我院上报的113例中药制剂的ARDs报告,整理统计病例的年龄、性别、药品种类及剂量、给药途径、不良反应等。结果:113例ARDs报告中女性比例(59.3%)高于男性ARDs(40.7%),0~12岁小儿(37.2%)及>60岁老年人比例(46.9%)是ARDs的高发对象,给药方式以静脉滴注为主,2013—2015年ARDs比例依次为16.8%、34.5%、48.7%,ARDs临床表现主要在皮肤及附件(46.0%)、消化系统(19.5%)方面。结论:在中药制剂临床应用中ARDs的发生受多方面因素影响,包括年龄、性别、给药途径等,临床应充分认识到这些影响因素,采取全面有效的ARDs防范措施,保障中药制剂应用的安全性。更多还原

【Abstract】 Objective: To analyze the causes of adverse medicine reactions(ARDs) in the clinical application of Chinese medicine and to propose the preventive measures. Methods: According to age, gender, drug type and dosage, administration route, adverse reactions, the reports of 113 cases of Traditional Chinese Medicine treatment between 2013.5 to 2015.10 were retrospectively analyzed. Results: Among 113 cases with ARDs, female proportion(59.3%) was higher than that of male(40.7%), higherincidence of ARDs was observedin children aged 0~12(37.2%) and > 60 year old elderly proportion(46.9%), to give medicine to give priority to the intravenous drip, the proportion of ARDsin 2013,2014 and 2015 being 16.8%, 34.5% and 48.7%.Adverse reactions were mainly observed in skin and its accessories(46.0%), and digestive system(19.5%). Conclusion: The occurrence of ARDs during clinical application of Traditional Chinese medicine is affected by many factors such as age, gender, route of administration, etc. so these factors must be considered carefully to take effective measures to prevent ARDs, and to protect the safety of Chinese medicine application.更多还原