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贝那普利联合氨氯地平治疗高血压的降压效果观察

Antihypertensive Effect of Benazepril Combined with Amlodipine in the Treatment of Hypertension

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【作者】 黄宏伟王雁

【Author】 HUANG Hong-wei;WANG Yan;Third Affiliated Hospital of Xinxiang Medical University;

【机构】 新乡医学院第三附属医院浙江医院

【摘要】 目的:观察研究贝那普利与氨氯地平联合用于高血压治疗的降压效果。方法:抽选2014年9月-2015年9月本院接收的80例高血压患者,将其随机分成两组,一组为研究组共40例,采用那贝那普利+氨氯地平联合方案治疗,另一组为对照组共40例,采用氨氯地平单独用药方案治疗,对比两组血压控制效果、血压下降情况和不良反应情况。结果:研究组总有效率为95.00%,比对照组的70.00%高,差异有统计学意义(P<0.05);两组患者治疗后舒张压和收缩压均有所下降,研究组降压情况优于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异有统计学意义(P<0.05)。结论:采用贝那普利和氨氯地平联合方案治疗高血压可有效控制患者血压,降压效果好,且安全,是治疗高血压的有效治疗方案,推荐使用。

【Abstract】 Objective:To observe and study the antihypertensive effect of Benazepril combined with Amlodipine in the treatment of hypertension.Method:From September 2014 to September 2015 80 cases of hypertensive patients wereselected and randomly divided into two groups,agroup for the study group of 40 cases,using Benazepril+Amlodipine in combination with chemotherapy,another group was the control group of 40 cases,using Amlodipine monotherapy regimen,blood pressure control effects,blood pressure conditions and adverse reactions of two groups were compared.Result:The total effective rate of the study group was 95.00%,was higher than 70.00% of the control group,the difference was significant(P<0.05).DBP and SBP of two groups had declined,the study group was better than that of the control group,the difference was significant(P<0.05).Two groups were statistically significant differences in adverse events(P<0.05).Conclusion:Benazepril and Amlodipine in combination with chemotherapy in patients with hypertension can effectively control blood pressure,antihypertensive effect is good,and safe,is an effective treatment of hypertension treatment regimen recommended.

【关键词】 贝那普利氨氯地平高血压降压
【Key words】 BenazeprilAmlodipineHypertensionAntihypertensive
  • 【文献出处】 中国医学创新 ,Medical Innovation of China , 编辑部邮箱 ,2016年15期
  • 【分类号】R544.1
  • 【被引频次】7
  • 【下载频次】35
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