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舌下含服尘螨滴剂对变应性鼻炎的临床疗效观察
Observation of curative effect by sublingual administration of dust mites drops for allergic rhinitis
【摘要】 目的探究舌下含服尘螨滴剂对变应性鼻炎的治疗效果。方法 52例变应性鼻炎患者,采用舌下含服尘螨滴剂治疗,经过12个月的治疗后,观察治疗效果,对患者治疗前后症状与体征评分进行对比分析,并对不良反应情况准确统计。结果 52例患者治疗总有效率为78.85%;与治疗前相比,患者治疗后喷嚏、流涕、鼻痒以及鼻塞等症状与体征评分均明显降低,且症状体征总分也明显降低,差异均具有统计学意义(P<0.05);有4例患者产生局部不适感,有2例患者产生局部荨麻疹。结论舌下含服尘螨滴剂对变应性鼻炎的治疗效果显著,安全性较高,可改善患者的临床症状。
【Abstract】 Objective To investigate curative effect by sublingual administration of dust mites drops for allergic rhinitis. Methods There were 52 patients with allergic rhinitis receiving sublingual administration of dust mites drops for treatment. After treatment for 12 months, curative effect was observed, symptoms and vital signs were compared and analyzed, and adverse reactions were taken in accurate summary. Results Total effective rate in 52 cases was 78.85%. Comparing with those before treatment, patients had obviously reduced cough, rhinorrhoea, rhinocnesmus, rhinobyon and vital signs score, along with reduced total score of symptoms.The difference had statistical significance(P<0.05). There were 4 cases with local discomfort and 2 cases with local urticaria. Conclusion Sublingual administration of dust mites drops shows precise effect in treating allergic rhinitis, with high safety and improvement of clinical symptoms.
【Key words】 Dust mites drops; Sublingual administration; Allergic rhinitis; Curative effect;
- 【文献出处】 中国实用医药 ,China Practical Medicine , 编辑部邮箱 ,2016年14期
- 【分类号】R765.21
- 【下载频次】43