【摘要】 目的:研究补肾活血中药联合经皮椎体成形术治疗骨质疏松椎体压缩骨折的疗效优势。方法:纳入2013年6月至2015年6月接受椎体成形术治疗的骨质疏松椎体压缩骨折(OVCF)患者,影像及随访资料完整者54例。联合补肾活血方+PKP组共33例、39节椎体,单纯PKP组共21例、25节椎体。记录患者一般资料(年龄、性别、病程、骨密度、骨折节段分布等),手术相关信息(手术时间、骨水泥注入量等)。分别于术前、术后1周内、术后1~6个月随访视觉模拟疼痛VAS评分、功能障碍ODI评分和SF-36生活质量评分,分别作组间比较。结果:两组患者的年龄、性别构成比、骨密度、伤椎分布等均无差异。术前和术后1周内随访的VAS评分、ODI评分差异无统计学意义。术后14d及1个月、6个月随访的PKP+补肾活血中药组VAS,ODI,SF-36中四维度(PF,BP,VT,SF)评分较PKP组更好,差异有统计学意义。术后1个月和6个月随访中,PKP+补肾活血中药组在SF-36的另外两个维度(RP、GH)也显示出优势。结论:联合应用补肾活血中药有助于增强和保持椎体成形术治疗骨质疏松椎体压缩骨折的疗效,值得临床关注。更多还原

【Abstract】 Objective:To compare the curative effect between percutaneous kyphoplasty(PKP)and PKP combined with Bushen Huoxue decoction for osteoporotic vertebral compression fractures(OVCFs).Methods:We retrospectively selected 54 patients who underwent PKP for OVCFs between June 2013 to June 2015 with detailed follow-up information(39vertebral of 33 cases underwent PKP combined with Bushen Huoxue decoction and 25 vertebral of 21 cases underwent PKP).General clinical data,such as sex,age,clinical course,bone density,different segments of the fractures,etc,and surgical data,such as operation time,cement volume of all patients were recorded.The VAS score,ODI score,and SF-36 quality of life score were recorded and compared at 1week before surgery and 1week,1to 6months after surgery.Results:There was no significant difference in general data,such as age,sex,bone mineral density,and different segments of the fractures,between the two groups.There was no significant difference in the VAS score,ODI score,and SF-36 quality of life score between the two groups 1week before and after surgery.The score of VAS,ODI and SF-36(PF,BP,VT and SF)in the patients underwent PKP combined with Bushen Huoxue decoction were significantly better than the patients underwent PKP only at the 14 th days,1st month,and 6th months after surgery.And the score of SF-36(RP and GH)in the patients underwent PKP combined with Bushen Huoxue decoction were also significantly better than the patients underwent PKP at the 1st and 6th months after surgery.Conclusion:The PKP combined with Bushen Huoxue decoction is more effective for treating OVCFs compared with PKP only.更多还原