【摘要】 目的探讨血清降钙素原(PCT)、超敏C反应蛋白(hs CRP)和白细胞计数(WBC)在小儿呼吸道感染病原诊断中的价值。方法选取广东省中医院儿科143例呼吸道感染患儿作为研究对象,按感染病原分为病毒组(42例)、支原体组(45例)和细菌组(56例)。其中细菌组包括革兰阳性(G~+)菌组27例,革兰阴性(G~-)菌组29例。分别检测各组血清PCT、hsCRP及WBC,并进行统计学分析。结果细菌组PCT、hsCRP及WBC水平均明显高于病毒组和支原体组(P<0.05),G~-菌组PCT水平明显高于G~+菌感染组(P<0.01)。PCT用于诊断细菌感染和G-菌感染的ROC曲线下面积大于hsCRP和WBC。结论PCT、hsCRP和WBC检测可初步判断小儿呼吸道疾病病原类型且PCT的诊断价值优于hsCRP和WBC。更多还原

【Abstract】 Objective To explore the value of serum procalcitonin(PCT),hypersensitive C- reactive protein( hsCRP),and white blood cell( WBC) count in etiological diagnosis of children with respiratory tract infection. Methods A total of 143 children with respiratory tract infection were selected from Department of Pediatrics in the hospital and divided into viral infection group(42 children),mycoplasma infection group(45 children),and bacterial infection group(56 children). The children in bacterial infection group were further divided into Gram positive bacteria subgroup(27 children) and Gram negative bacteria subgroup(29 children). Serum levels of PCT,hsCRP,and WBC were detected and analyzed statistically. Results The levels of PCT,hsCRP,and WBC in bacterial infection group were statistically significantly higher than those in viral infection group and mycoplasma infection group(P<0. 05); PCT level in Gram negative bacteria subgroup was statistically significantly higher than that in Gram positive bacteria subgroup(P<0. 01).The area under ROC of PCT for diagnosing bacterial infection and Gram negative bacteria infection was larger than those of hsCRP and WBC. Conclusion PCT,hsCRP,and WBC can preliminarily estimate the etiological types of respiratory tract infection in children,the diagnostic value of PCT is better than hsCRP and WBC.更多还原