【摘要】 目的研究淡黄香茶菜Isodon flavidus枝叶的化学成分。方法采用硅胶、Sephadex LH-20、MCI等色谱材料及方法分离纯化,通过理化性质和波谱数据鉴定化合物的结构。结果从淡黄香茶菜枝叶95%乙醇提取物中分离得到9个化合物,分别鉴定为线纹香茶菜酸(1)、isopimara-7,15-dien-19-oic acid(2)、isopimara-7,15-dien-3β-ol(3)、rubesanolide D(4)、乌索酸(5)、β-谷甾醇(6)、齐墩果酸(7)、2α,3α-二羟基-12-烯-28-乌索酸(8)、芝麻素(9)。结论化合物1~5、8~9为首次从该植物中分离得到,化合物3为首次从该属植物中分离得到。更多还原

【Abstract】 Objective To investigate the chemical constituents of Isodon flavidus. Methods All compounds were isolated and purified by silica gel, Sephadex LH-20, and MCI column chromatography. Their structures were elucidated by analysis on the physicochemical properties and spectral data. Results Nine compounds were obtained from the Miao medicine I. flavidus and respectively elucidated as lophanic acid(1), isopimara-7,15-dien-19-oic acid(2), isopimara-7,15-dien-3β-ol(3), rubesanolide D(4), ursolic acid(5), β-sitosterol(6), oleanolic acid(7), 2α,3α-dihydroxy-12-ene-28-oic acid(8), and sesamin(9). Conclusion Compounds 1—5 and 8—9 are isolated from this plant for the first time, compound 3 is isolated from the plants of Rabdosia(BL.) Hassk for the first time.更多还原