【摘要】 目的分析安徽省2000-2014年疫苗相关麻痹型脊髓灰质炎病例(VAPP)的流行病学特征。方法查阅2000-2014年安徽省VAPP的相关资料,用描述性流行病学研究方法,分析相关指标,找出其流行病学特征。结果 2000-2014年安徽省共报告46例VAPP,2003年和2011年发生的VAPP病例数最多,占15.22%和10.87%;服苗者VAPP与接触者VAPP发生年龄差异有统计学意义(χ~2=10.460,P<0.05);病毒学检测结果显示,脊灰疫苗Ⅱ型病毒株30例,较其他2种型别的检出率为高(χ~2=10.240,P<0.05)。结论在维持无脊髓灰质炎后期,应制定出科学,可行的免疫措施,以减少VAPP的发生。更多还原

【Abstract】 Objective This work was to analyze the epidemiological characteristics of VAPP in Anhui Province during 2000-2014 Methods The relevant data of VAPP in Anhui province from 2000-2014 were collected and analyzed using descriptive epidemiology research method for the epidemiological characteristics. Results A total of 46 cases of VAPP were reported in Anhui Province during 2000-2014. Incidence was higher in 2003 and 2011, accounting for 15.22% and 10.87%,respectively. Significant difference in the onset age was observed between the VAPP patients received corresponding vaccination and those with exposure contact(χ~2=10.460,P<0.05). By viral detection, 30 cases were of the Polio vaccine virus Type II, with a higher detection rate in comparison to the other two types(χ~2=10.240,P<0.05). Conclusion In the late period of polio eradication, a scientific, feasible immune measure should be made to reduce the occurrence of VAPP.更多还原