【摘要】 目的了解西安市男男性行为者(MSM)艾滋病病毒(HIV)感染情况,估算该人群中的HIV新发感染率。方法 2013-2015年通过四轮横断面调查,对2441例MSM进行问卷调查及血清学检测,对HIV阳性的样本,再进行BED HIV-1IgG捕获酶免疫法(BED-CEIA)检测,以此估算该人群的新发感染率。结果 2441例MSM的平均年龄为(28.95±7.52)岁(16~70岁);未婚占69.8%,汉族占99.2%,陕西省户籍占84.2%,在当地居住时间2年以上占81.3%,文化程度大专及以上占78.1%,认为自己是同性恋的占73.4%,最主要交友场所为网络/交友软件的占83.6%,艾滋病知识知晓率为85.8%。共筛查出HIV阳性179例,筛查阳性率7.33%,接受BED检测的158例样本中,71例为新近感染,四轮调查的新发感染率分别为7.20%[95%可信区间(CI):3.41%~10.99%]、9.18%(95%CI:5.06%~13.31%)、6.85%(95%CI:3.09%~10.60%)、4.88%(95%CI:1.84%~7.92%),合计新发感染率为7.00%(95%CI:5.11%~8.90%)。近六个月与临时性伴发生同性性行为是否使用安全套、近六个月是否使用如RUSH的助性剂、近一年是否接受过HIV检测、梅毒检测结果4个因素,对MSM新近感染HIV有统计意义(P<0.05)。结论西安市艾滋病防治各种干预检测工作对疫情的控制是有效的,但仍需继续加强干预检测力度,遏制艾滋病疫情向一般人群的蔓延。更多还原

【Abstract】 Objective To analyze human immunodeficiency virus(HIV)infection situation of men who have sex with men(MSM),and estimate HIV incidence among MSM.Methods 4cross-sectional sentinel surveys were conducted during 2013-2015,and 2441 MSM were investigated and received serological tests.HIV positive samples were tested with BED HIV-1IgG capture enzyme immunoassay(BED-CEIA)to estimate HIV incidence in MSM.Results The average age of 2441 cases was 28.95±7.52(16-70),69.8% was unmarried,99.2% was Han,84.2% was registered residence of Shaanxi province,81.3% was living in the province more than two years,78.1% had college education level or above,73.4%considered themselves as homosexual,83.6% preferred making friends online.HIV/AIDS knowledge awareness was 85.8%.179 cases were screened as HIV positive,with the rate of 7.33%.158 screened HIV positive samples accepted BED test and 71 cases were found newly infected,with the incidences of 7.20%(95%CI:3.41%-10.99%),9.18%(95%CI:5.06%-13.31%),6.85%(95%CI:3.09%-10.60%),4.88%(95%CI:1.84%-7.92%)respectively.The total HIV incidence rate was 7.00%(95%CI:5.11%-8.90%).Condom use with temporary anal sexual partners last 6months,rush popper use last 6months,HIV test last year and result of syphilis test were influence factors of HIV new infection.Conclusion The AIDS prevention measures are effective in Xi’an,but intervention still needs to be strengthened to contain HIV spreading.更多还原