【摘要】 目的了解乙型肝炎、肝硬化和肝癌的死亡率和变化趋势,估计3种疾病的潜在寿命损失。方法利用2009—2014年居民死因监测报告数据,分析各年份的粗死亡率、标化死亡率、年龄别死亡率、潜在减寿年数(PYLL)、减寿率(PYLL‰)和平均减寿年数(AYLL)等指标。结果 2009—2014年江苏省传染病综合防治示范区居民乙型肝炎(乙肝)和肝硬化的死亡率下降趋势明显,肝癌的死亡率维持稳定。男性肝癌的死亡率显著高于女性,<60岁人群乙肝相关疾病的死亡率逐年下降,>60岁人群死亡率呈上升趋势,乙肝死亡的高峰年龄呈逐年后移趋势。2009—2014年示范区居民乙肝、肝硬化和肝癌患者的平均寿命损失年(AYLL),分别为16.86、13.21、14.23年/人。结论目前示范区所实施的乙肝防控措施取得了良好效果,应继续加强成人乙肝疫苗接种及慢性乙肝病人规范化治疗工作,以降低死亡率和疾病负担。更多还原

【Abstract】 Objective To analyze the mortality and epidemiological trend of hepatitis B,liver cirrhosis and liver cancer mortality of different genders,to evaluate potential years of life lost caused by the three diseases.Methods Indices such as crude mortality,standardized mortality,mortality of different genders,potential years of life lost(PYLL),rate of PYLL(PYLL‰),average years of life lost(AYLL)were used to analyze data obtained from death surveillance of Jiangsu province from 2009 to 2014.Results The mortality of hepatitis B and liver cirrhosis significantly decreased from 2009 to 2014,while the mortality of liver cancer had a steady tendency.The mortality of men was higher than that of women for liver cancer.The yearly mortality rate of the three diseases showed an descendirg trend among population below 60 years old,while an increasing trend among the age group over 60 years old.Average age peaks of death increased.AYLL of hepatitis B,liver cirrhosis and liver carcer were 16.86,13.21 and 14.23years/person,respectively.Conclusion The current prevention and control strategy of hepatitis B showed a good effect in demonstration area.Hepatitis B vaccination in adults and standardized treatment in chronic hepatitis B patients should be enhanced to reduce the mortality and burden of hepatitis B related disease.更多还原