【摘要】 目的探讨冠心病猝死Tp-e间期延长的检测与临床意义。方法选取冠心病患者502例,其中冠心病猝死46例,设为猝死组,其余456例患者设为存活组。比较两组患者Tp-e、Tp-e/姨RR、按心率校正的QT间期(QTc)、左室射血分数(LVEF)的差异,并判断Tp-e间期延长对冠心病猝死的临床意义。结果与存活组比较,猝死组患者Tp-e、Tp-e/姨RR和QTc明显延长(P<0.05);与存活组比较,猝死组患者LVEF明显降低(P<0.05);Tp-e延长与冠心病猝死、QTc呈正相关(P<0.05)。结论冠心病猝死患者Tp-e间期明显延长,Tp-e间期延长可能成为冠心病猝死的危险预测指标。更多还原

【Abstract】 Objective To investigate the detection and clinical significance of Tp-e interval extension of sudden coronary death. Methods A total of 502 patients with coronary heart disease were selected,of which 46 patients with sudden coronary death were assigned to the sudden death group and the other 456 patients were assigned to the survival group. The Tp-e,Tp-e/ 姨RR,heart rate-corrected QT inverval(QTc) and left ventricular ejection fraction of the two groups were compared and the clinical significance of Tp-e interval extension for sudden coronary death was decided.Results Compared to the survival group,the sudden death group had significantly extended Tp-e,Tp-e/ (1/2)RR and QTc(P<0.05); Compared to the survival group,the sudden death group had significantly reduced LVEF(P<0.05); Tp-e extension was positively correlated to sudden coronary death and QTc(P<0.05). Conclusion The Tp-e interval extended obviously in the patients with sudden coronary death and thus can serve as a predictive risk factor of sudden coronary death.更多还原