【摘要】 组织工程皮肤从概念提出至今技术发展迅速.本文对现有的组织工程皮肤进展展开论述,组织工程皮肤主要分3大类:由种子细胞和支架材料体外三维构建培养的组织工程皮肤、由细胞组成的组织工程化皮肤和由支架材料构成的组织工程化皮肤,根据其结构组成、形态或来源又分成2~3种,每种选1~3个代表具体描述.然后针对现有组织工程存在的再生修复性能不足、细胞来源受限、生产运输成本过高等技术问题进行分析讨论,同时就目前国家对该领域的管理办法进行了讨论和建议,并提出了组织工程皮肤的一些非移植性扩展应用.通过对组织工程皮肤领域技术成果的总结、技术问题与现有研究热点的讨论和未来前景的分析,希望能更好地促进该领域发展.更多还原

【Abstract】 Tissue engineering skin(TE Skin) technology has been developed rapidly from the beginning to now. In this review, products of TE Skin are classified into 3 types: TE Skin composed of cells and scaffold, TE Skin from cells only, TE Skin form with several scaffold materials. Each type of TE Skin was divided into 2 or 3 categories according to structure, morphology and origin, and representative products of every category were given specific description. Insufficent capacity of regeneration and repairing, limited cell sources, the high cost of maufacture and transportation, discussion and analysis of existing problems in TE Skin are conducted. Management of TE Skin is also discussed, and some extended applications of TE Skin are proposed, such as cosmetic test kit. Through summing up technical achievements, discussion of research focuses and analysis of future prospects, we hope this review to help understand the field TE Skin.更多还原