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纵隔髓外造血瘤样增生疾病的临床探讨

Clinical study of extramedullary hematopoiesis in the mediastinum: literature analysis and a case report

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【作者】 梁登峰张东升陈敏东陈曲海徐子迅

【Author】 Liang Dengfeng;Zhang Dongsheng;Chen Mindong;Department of Cardiothoracic Surgery,the First People’s Hospital of Guangzhou;

【机构】 广州市第一人民医院心胸外科

【摘要】 目的探讨纵隔髓外造血(EMH)的临床特点,从而为其诊断、治疗提供参考意见。方法总结分析我科收治的1例双侧后纵隔骨髓外造血组织多发瘤样增生,并对近10年来国内相关文献报道的27例病例进行回顾性分析。结果患者需行手术活检取得病理诊断,确诊髓外造血。结论纵隔髓外造血瘤样增生是一种罕见特殊的良性病变,预后良好。但因其临床表现和影像学均缺乏特异性,当临床中遇到发生在后纵隔脊柱旁的占位性病变,同时患有贫血的患者应考虑EMH的可能性,给予经皮穿刺或者胸腔镜下活检来取得细胞学诊断,从而避免不必要的手术治疗。

【Abstract】 Objective To probe into the clinical features of mediastinal extramedullary hematopoiesis( EMH),for providing a reference for clinical diagnosis and treatment. Methods The clinical data was studied in a case of mediastinal EMH from our department, and 27 case reports from domestic published literatures over the last decade were analyzed retrospectively. Results Of the 27 patients,15 received surgical excision,while the other 12 underwent needle biopsy. In our patient,the diagnosis of EMH was made by mini thoracotomy and open biopsy. Conclusion Mediastinal EMH is a rare disease and its prognosis is well. Because there is no obvious specific clinical symptoms and imaging appearances,the possibility of EMH should be considered when a patient with a mediastinal tumor associated with anemia is encountered. Diagnosis can be achieved by needle biopsy or video-assisted thoracic surgery( VATS) in order to prevent unnecessary surgical procedures.

  • 【文献出处】 广州医药 ,Guangzhou Medical Journal , 编辑部邮箱 ,2015年06期
  • 【分类号】R734.5
  • 【下载频次】79
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