【摘要】 结核病是严重危害人类生命健康的历史最悠久的疾病之一,近年来耐药结核病呈上升趋势。乙胺丁醇是治疗结核病,尤其是耐多药结核病的重要药物,但是随着该药的长时间使用,其耐药情况逐步出现,目前已有大量报道。为此笔者综述了乙胺丁醇分子耐药机制的研究进展。更多还原

【Abstract】 Tuberculosis is one of the oldest infectious diseases that put great threat to the human life.Ethambutol(EMB)is one of the most important anti-tuberculosis drugs for the drug sensitive and multidrug resistant tuberculosis.With the long time use of this drug EMB-resistant Mycobacterium tuberculosis is on the rise and being reported all over the world.This article reviewed the research progress in molecular mechanism of EMB resistance.更多还原