【摘要】 [目的]探讨化疗对晚期胃癌中医证型的影响。[方法]通过前瞻性研究,对2012年6月1日至2013年11月1日在浙江省中医院肿瘤科、浙江大学第一附属医院肿瘤科住院治疗的50例晚期胃癌患者进行化疗前后的中医辨证分型,将收集的数据建立数据库,运用SPSS 17.0进行统计学分析。[结果]晚期胃癌患者化疗前以气血亏虚型、痰湿凝结型以及气滞血瘀型居多,分别占24%、20%、22%,两个化疗周期完成后证型分布虚证以气血两虚型、脾胃虚寒型为主,分别占34%、24%,实证则以痰湿凝结型多见,占16%。其中化疗后脾胃虚寒证增加,气滞血瘀证型减少,差异具有统计学意义(P<0.05)。[结论]晚期胃癌患者化疗前以气血亏虚型、痰湿凝结型以及气滞血瘀型居多,化疗后以气血两虚型、脾胃虚寒型及痰湿凝结型多见。研究结果对晚期胃癌的中医诊断、治疗措施选择、指导患者康复等方面有积极意义。更多还原

【Abstract】 [Objective]To investigate the influence of chemotherapy on advanced gastric cancer’s traditional Chinese medicine(TCM) syndromes. [Methods]50 cases of advanced gastric cancer patients were treated with chemotherapy.Then observed the differentiation of TCM syndromes of the patients before and after chemotherapy.The data were analyzed by SPSS17.0. [Results]Before chemotherapy,patients were in deficiency of Qi and blood,stagnation of phlegm damp and Qi stagnation and blood stasis syndrome,accounted for 24%,20%,22% respectivey. After two cycles of chemotherapy,demonstration syndromes were deficiency of Qi and blood,deficiency cold of spleen and stomach syndrome.Evil domination syndrome was stagnation of phlegm damp syndrome.[Conclusion]Before chemotherapy,deficiency of Qi and blood,Stagnation of phlegm damp and Qi stagnation and blood stasis syndromes were the most syndromes.But after chemotherapy,the most syndromes were deficiency of Qi and blood,Qi stagnation and blood stasis and deficiency cold of spleen and stomach syndrome.更多还原