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磁共振斑块成像技术临床应用的现在与未来

Present and Future of Clinical Application of Magnetic Resonance Plaque Imaging Techniques

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【作者】 赵锡海宋焱李飞宇苑纯

【Author】 ZHAO Xi-Hai;SONG Yan;LI Fei-Yu;YUAN Chun;Center for Biomedical Imaging Research, Tsinghua University;

【机构】 清华大学生物医学影像研究中心北京医院放射科北京大学第一医院放射科美国华盛顿大学放射系血管成像实验室

【摘要】 磁共振斑块成像技术已被广泛应用于颈动脉粥样硬化斑块特征的研究中。经组织学验证,这些技术能够准确评价斑块负荷、组织成分、纤维帽完整性和炎症反应。本综述将从以下几个方面阐述磁共振斑块成像技术在临床实践中的潜在应用价值:①在易损斑块表面破裂前,磁共振斑块成像能够对其进行早期识别,从而预防缺血性卒中;②颈动脉斑块磁共振特征可能有助于制订临床治疗策略;③磁共振斑块成像是监测颈动脉粥样硬化病变他汀类药物治疗效果的有效手段。

【Abstract】 Magnetic resonance(MR) plaque imaging techniques have been widely used to characterize carotid atherosclerotic plaques. These techniques are capable of accurately evaluating plaque burden measurements, tissue compositions, integrity of fibrous cap and inflammation with histological validation. This review will describe the potential roles of MR plaque imaging techniques in clinical practice from the following aspects: for prevention of ischemic stroke, MR plaque imaging can be used to early detect vulnerable plaques prior to surface disruption; characteristics of carotid plaques determined by MR plaque imaging might be helpful in making strategy of carotid revascularization; MR plaque imaging is a useful tool for monitoring treatment effect of statin in carotid atherosclerosis.

  • 【文献出处】 中国卒中杂志 ,Chinese Journal of Stroke , 编辑部邮箱 ,2014年02期
  • 【分类号】R445.2;R743.3
  • 【被引频次】6
  • 【下载频次】321
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