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2006-2012年佛山市某院441 867例住院患者HIV抗体筛查结果分析
Analysis of HIV Antibody Screening in 441 867 Inpatients of One Hospital of Foshan between 2006 and 2012
【摘要】 目的探讨佛山市第一人民医院住院患者中人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染的流行病学及临床特征。方法对2006年1月-2012年12月期间的441 867例住院患者进行HIV抗体的检测,阳性者标本送佛山市疾控中心行HIV抗体确证试验,同时进行T淋巴细胞亚群计数,TRUST,TPPA,HCV及相关病原体检测。回顾分析住院病历资料。结果筛查发现HIV/AIDS患者168例,检出率0.38‰(168/441 867),2010年前感染人数逐年上升,2010年后出现下降。男女之比为2.43∶1,年龄分布以20~39岁(52.98%)为多,性传播为主要传播途径(79.17%),75例合并机会性感染(44.64%):真菌感染31例(18.45%),严重细菌感染22例(13.10%),结核分枝杆菌感染12例(7.14%)。共有17例患者死亡,主要死亡原因为感染。结论自2010年起,佛山地区HIV感染情况开始有所好转,对住院患者进行HIV抗体的检测是发现HIV感染的重要途径,机会性感染是其主要临床特征及死亡原因,临床医生必须提高对HIV/AIDS的警觉性。
【Abstract】 Objective To investigate the epidemiology and clinical features of human immunodeficiency virus( HIV) infection in inpatients of the First People’s Hospital of Foshan. Methods HIV antibody was tested in 441 867 cases of in patients between January 2006 and December 2012. Positive serum was sent to the CDC of Foshan to confirm. Positive cases had the T lymphocyte subgroup counted,TRUST,TPPA,HCV test and the detection of correlation infection. Review and analysyze the clinical data of HIV / AIDS patients. Results The total first-diagnosed HIV / AIDS cases by HIV antibody screening were 168,the positive rate was 0. 38‰( 168 / 441 867). The epidemic situation of HIV / AIDS presented the accelerating upward trend from 2006 to 2010, but after 2010,it was descending. The male to female ratio was 2. 43 ∶ 1. The age group of 20 ~ 39( 52. 98%) outnumbered other groups. The sexual contact was the major route of transmission( 79. 17%). Seventy-five cases had the opportunistic infections: 31 cases( 18. 45%) were fungous infection,22 cases( 13. 10%) were serious bacteria infection,12 cases( 7. 14%) were tuberculosis. There were 17 cases died, the major of them died from infection. Conclusion In Foshan area,the epidemic situation of HIV / AIDS present the descending trend from 2010. The test of HIV antibodies is an important way to screen the HIV / AIDS patients in inpatients of general hospital. The symptoms of opportunistic infection are the major clinical appearance and the cause of death. Therefore,the clinicians must pay more attention to AIDS / HIV infection.
- 【文献出处】 中国皮肤性病学杂志 ,The Chinese Journal of Dermatovenereology , 编辑部邮箱 ,2014年04期
- 【分类号】R512.91
- 【被引频次】5
- 【下载频次】63