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胃癌病因学的研究进展
Research Progress of Gastric Cancer Etiology
【摘要】 胃癌是危害人类生命健康的主要恶性肿瘤之一,其病因很复杂,涉及多个危险因素和众多基因的改变。胃癌的发生与遗传、病原体感染、生活方式、精神因素、癌前状态、地球化学因素、年龄和性别、ABO血型等有关,其分子机制与DNA高甲基化、微卫星不稳定有关。现对近年来胃癌病因学方面的新进展进行重点论述。
【Abstract】 Gastric cancer is one of the major health hazards to human life,and its etiology is complex,involving multiple risk factors and changes in numerous genes. The gastric carcinogenesis is related to hereditary,athogenic infections,lifestyles,mental factors,precancerous condition,geochemical factors,age,gender and ABO blood group. Molecular mechanism is relevant to gene methylation and microsatellite instability.Here is to make a review of the new progress of gastric cancer etiology in recent years.
- 【文献出处】 医学综述 ,Medical Recapitulate , 编辑部邮箱 ,2014年14期
- 【分类号】R735.2
- 【被引频次】63
- 【下载频次】1416