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进展期胃癌术前介入治疗的临床应用

Advanced gastric cancer of preoperative inter ventional therapy for dinical application

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【作者】 孙宾; 李兴; 宋杰; 蒋天鹏; 贺晓燕; 周石;

【Author】 SUN Bin;LI Xing;SONG Jie;JIANG Tianpeng;HE Xiaoyan;ZHOU Shi;Department of Radiology,the Affiliated Hospital of Guiyang Medical College;

【机构】 贵阳医学院附属医院放射科; 贵阳医学院附属肿瘤医院病理科;

【摘要】 目的 探讨术前介入经动脉灌注化疗栓塞治疗和术前经静脉全身单纯化疗治疗胃癌的疗效。方法 回顾分析确诊胃癌的55例患者,分为治疗组及对照组(单纯化疗组)。治疗组35例,对照组20例,2组病例均接受胃癌外科根治手术治疗,观察术前及术后临床症状的改善,肿瘤病灶的大小、肿瘤血管改变等资料进行分析比较,观察2组疗效之间的差异。结果 与对照组比较,治疗组胃癌组织中肿瘤细胞变性坏死明显,肿瘤细胞体积缩小,肿瘤血管明显减少、不均匀、变薄。治疗组肿瘤血管数目明显低于对照组(P<0.05)。结论 胃癌介入治疗短期治疗效果明显,能有效地使肿瘤血管减少,提高手术切除率。

【Abstract】 Objective To investigate the curative effect of the preoperative intervention transcatheter arterial chemoembolization and preoperative intravenous systemic simple chemotherapy for gastric cancer.Methods Retrospective analysis of 55 patients diagnosed with gastric cancer.These patients were divided into two groups:treatment group and control group(simple chemotherapy group),with treatment group of 35 cases and control group of 20 cases,and cases of two groups all received surgical radical surgery for gastric carcinoma treatment.Preoperative and postoperative clinical symptoms were observed.Data of tumor sizes and tumor vessel changes were analyzed and compared.The difference of curative effect between two groups was observed.Results Compared with control group,degeneration and necrosis of tumor cells in gastric cancer tissue of treatment group were obvious,and tumor vessels significantly reduced,with nonuniformed,and became thinner.Number of tumor vessels of treatment group was obviously lower than that of control group(P<0.05).Conclusion The interventional therapy of gastric cancer has obvious short-term therapeutic effects,and can reduce tumor vessels effectively and improve surgical resection rate.

【关键词】 胃癌; 介入治疗;
【Key words】 gastric cancer; interventional therapy;
  • 【文献出处】 实用放射学杂志 ,Journal of Practical Radiology , 编辑部邮箱 ,2014年12期
  • 【分类号】R735.2;R815
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