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慢性呼吸性酸碱平衡紊乱时肾调节能力的量化研究

Quantitative Study on the Regulation of Renal Regulating Capacity of Chronic Respiratory Acid-base Balance Disturbance

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【作者】 王桂杰张海鹏

【Author】 WANG Gui-jie;ZHANG Hai-peng;Department of Mathematics,College of Basic Medical Sciences,China Medical University;Department of Pathophysiology,College of Basic Medical Sciences,China Medical University;

【机构】 中国医科大学基础医学院数学教研室中国医科大学基础医学院病理生理教研室

【摘要】 在慢性呼吸性酸碱平衡紊乱研究中,引入一新的概念,即顺应性C=Δ[HCO3-]/ΔPaCO2,它的变化范围大小能够描述肾调节能力的大小.为了将肾调节能力进行了量化,以X=PaCO2为自变量,Y=C=Δ[HCO3-]/ΔPaCO2为因变量,分别绘制出顺应性C=Δ[HCO3-]/ΔPaCO2范围中左端点和右端点的散点图,并求出其拟合曲线方程及其变化率,这种定量方法为进一步深入研究肾的调节能力提供依据.

【Abstract】 In study of disorder of chronic respiratory acid-base balance,by introducing a new concept,that is the complianceC =(△[HCO3-])/(△PaCO2),Changes in the scope of its size can be used to describe the renal regulating capacity.In order to quantify renal regulation ability,taking X = PaCO2 as variables,the Y = C =(△[HCO3-])/(△PaCO2) as the dependent variable,Scatter diagram of the compliance C =(△[HCO3-])/(△PaCO2)range about the left and right end point were drawn out in fig.,and find out the fitting curve equation and its rate of change.The quantitative method will provide the basis for further study of renal regulation ability.

【基金】 辽宁省自然科学基金(201102249)
  • 【文献出处】 数学的实践与认识 ,Mathematics in Practice and Theory , 编辑部邮箱 ,2014年24期
  • 【分类号】R589.6
  • 【下载频次】58
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