【摘要】 β-胡萝卜素是一种典型的类胡萝卜素,也是生物体内合成VA的前体物质,广泛应用于化工、化妆品、饲料、食品、保健品以及医药等行业。与化学合成的产品相比,天然β-胡萝卜素具有更好的生物活性且无毒副作用,因此具有更为广阔的应用空间。三孢布拉氏霉发酵产β-胡萝卜素过程不受光照、气候、产地等环境条件的限制,因此逐渐成为获取天然β-胡萝卜素的主要方法。本文从菌种选育、发酵工艺优化以及反应器等不同角度,对三孢布拉氏霉发酵生产β-胡萝卜素的相关研究进行概述,从而对该技术的优势和发展方向进行展望。更多还原

【Abstract】 β-Carotene, a typical representative of carotenoids, is the main source of pro-vitamin A. It has been widely used in chemical, cosmetic, feed, food, nutraceutical, pharmaceutical and other industries. Natural β-carotene has wider applications for its safety and bioavailability compared with the synthesized one. Among all comme rcialized natural β-carotene sources, microbial sources of β-carotene are much preferred due to its economical process and less limitation of environment factors, such as light, climate, producing region, etc. The present review is focused o n the current advances in the view points of strain breeding, fermentation optimization, and bioreactor development, which will enhance our understanding of this bioprocess.更多还原