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消栓肠溶胶囊治疗脑梗死稳定期临床观察

Clinical observation of “Xiaoshuan Changrong Capsule” for the treatment of cerebral infarction of stable stage

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【作者】 俞建洪查渭叶关胜方央沈红枫傅苏娜孙奇华

【Author】 YU Jian-hong;ZHA Wei;YE Guan-sheng;FANG Yang;SHEN Hong-feng;FU Su-na;SUN Qi-hua;Sixth People’s Hospital of Shaoxing;

【机构】 浙江省绍兴市第六人民医院老年科

【摘要】 目的观察消栓肠溶胶囊治疗脑梗死的临床疗效。方法将65例脑梗死稳定期患者随机分为两组;对照组30例口服阿司匹林片治疗,治疗组35例口服阿司匹林片和消栓肠溶胶囊治疗,疗程4周。观察两组治疗前后血液流变学和椎-基底动脉血流变化情况。结果治疗组总有效率为94.3%,对照组为66.7%;两组临床疗效比较差异有统计学意义(P<0.05)。治疗组血液流变学指标较治疗前显著降低(P<0.05),对照组仅全血黏度较治疗前降低(P<0.05);治疗后两组间血液流变学指标有显著差异(P<0.05)。治疗后两组椎动脉和基底动脉血流速度均较治疗前加快(P<0.05),且治疗组优于对照组(P<0.05)。结论消栓肠溶胶囊可提高治疗脑梗死的临床疗效,改善血流状态。

【Abstract】 Objective To observe the curative effect of"Xiaoshuan Changrong Capsule"in the treatment of cerebral infarction. Methods Sixty-five cases with cerebral infarction in stable phase were randomized into two groups: 30 cases in the control group were treated by asprin tablets,and 35 cases in the treatment group were treated by asprin tablets and"Xiaoshuan Changrong Capsule",with the course of 4 weeks. The changes of hemorheology and vertebral-basilar artery were observed. Results The total effective rate was 94. 3% in the treatment group and 66. 7% in the control group,with a difference between the two groups( P< 0. 05). The hemorheology indexes was lowered in the treatment group( P < 0. 05),only blood viscosity was lowered in the control group( P < 0. 05); after treatment,there was a significant difference in hemorheology indexes between the two groups( P < 0. 05); after treatment,the blood flow velocity of vertebralbasilar was accelerated in both groups( P < 0. 05),and with significant difference between the two groups( P < 0. 05). Conclusion "Xiaoshuan Changrong Capsule"can improve the clinical efficacy and blood flow in patients with cerebral infarction.

  • 【文献出处】 上海中医药杂志 ,Shanghai Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2014年09期
  • 【分类号】R277.7
  • 【被引频次】5
  • 【下载频次】120
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