【摘要】 目的探讨不同药物应用于全麻后催醒的临床效果及对血流动力学参数的影响。方法选择我院收治的105例静吸复合全身麻醉下择期腹部手术患者,按照分层随机分组法分为观察组63例和对照组42例,对照组术后催醒给予氟马西尼,观察组在对照组基础上加用参附注射液,观察两组催醒效果及血流动力学参数变化。结果观察组BIS评分、OAA/S评分、清醒时间及拔管时间等催醒效果观察指标均显著优于对照组,两组比较差异有统计学意义(P<0.05);观察组血压、心率、呼吸频率及平均脉动压与对照组比较差异无统计学意义(P>0.05),但观察组潮气量、血氧饱和度及不良反应发生率均显著优于对照组,两组比较差异有统计学意义(P<0.05)。结论参附注射液能显著提高全麻术后催醒的临床效果,在临床应用中具有重要价值。更多还原

【Abstract】 Objective To explore the analeptic effect of different drugs in patients emerging from general anesthesia and the effect of on hemodynamics. Methods According to a stratified randomization method,105 patients undergoing elective abdominal surgery under general anesthesia w ere divided into observation group( n = 63) and control group( n = 42),control group w as given flumazenil to w ake,observation group w as given Shenfu injection on the basis of control group,the analeptic effect and hemodynamic parameters w ere observed. Results The observation group w ere significantly better than the control group in the BIS score,the aw akening time,extubation time and other indicators,there w as significant difference betw een the tw o groups( P < 0. 05); there w as no significant difference in HR,blood pressure,RR and MAP betw een the tw o group( P > 0. 05); how ever,the observation group w as significantly better than the control group in tidal volume,SpO2and the incidence of adverse reactions,there w as significant difference betw een the tw o groups( P < 0. 05). Conclusion Shenfu injection can make patients emerging from general anesthesia aw ake faster,it has important clinical value.更多还原