【摘要】 目的了解河南省15岁以下儿童急性弛缓性麻痹病例(acute flaccid paralysis,AFP)流行学特征,为其防控策略制定提供科学依据。方法对河南省2004-2011年急性弛缓性麻痹病例监测系统报告15岁以下AFP病例进行描述性分析。结果河南省2004-2011年共发生15岁以下AFP病例4 500例,主要表现为散发。年平均发病率为2.95/10万,郑州市发病率最高4.96/10万,其次为三门峡市4.66/10万。发病高峰多出现于每年3月和8~10月,0~4岁组发病率较高,男性发病率高于女性,男女性别比为2.14∶1。741例AFP病例分离出肠道病毒,肠道病毒分离率为16.47%。15.80%的病例麻痹60 d有残留麻痹。结论河南省15岁以下儿童AFP病例以小年龄组为主,发病高峰多出现于春季、夏秋季,男性发病率高于女性,儿童AFP病例残留麻痹率较高,应及时采取措施降低致残率。更多还原

【Abstract】 Objective To analyze the epidemiological characteristics of acute flaccid paralysis( AFP) below 15 years of age in Henan Province and explore measures for AFP control and prevention. Methods The individual data of AFP cases under 15 years of age from surveillance system of Henan Province during 2004- 2011 was analyzed. Results4 500 cases of AFP among children under 15 years were reported in 2004- 2011 in Henan Province. The cases were mainly sporadic and the average incidence was 2. 95 /100 000. Zhengzhou City had the highest incidence of 4. 96 /100 000,by followed Sanmenxia City with 4. 66 /100 000. March and August to October each year were the peak seasons of AFP occurrence and the highest incidence was 0 to 4 years old group. Gender ratio was 2. 14 ∶ 1. Enterovirus was isolated from 741 cases and the rate was 16. 47%. The incidence rate of residual paralysis was 15. 80%. Conclusions AFP is mainly seen in young people and the cases are mainly observed in spring,summer and autumn. Effective measures should be taken to improve the recovery of paralysis.更多还原