【摘要】 为获得含量较高的马兰草生物碱,对马兰草总生物碱的提取工艺条件进行了优化,探讨了乙醇浓度、温度、时间和料液比对总生物碱提取的影响,并研究了其对羟基自由基的清除效果。结果表明:马兰草总生物碱的最佳提取工艺为乙醇浓度40%,温度为50℃,料液比1∶25(g/mL),提取时间为75min。在该条件下的总生物碱含量为3.33mg/g,提取液对羟自由基具有一定的清除能力,当提取液生物碱浓度为0.040 0mg/mL时,对·O H的清除率达到42.08%。更多还原

【Abstract】 To study on optimal conditions for extracting high concentration of total alkaloid from K.indical,the effects of ethanol concentration,temperature,time and solid-liquid ratio on exacting total alkaloid were explored and the cleanup effect on hydroxyl radical was studied either.The results showed that the optimum extraction conditions included 40% ethanol as extractant,temperature on 50℃, extraction time by 75min,ratio of material to liquid on 1∶25(g/mL).In this case,the total alkaloid could reach 3.33mg/g and the extracting solution has certain antioxidative effect.When the concentration of total alkaloid was 0.040 0mg/mL,the rate of scavenging hydroxyl radicals reached 42.08%.更多还原