【摘要】 目的分析肺炎克雷伯菌感染的临床分布与耐药情况,为临床医生合理使用抗菌药物提供理论依据。方法回顾分析各类标本肺炎克雷伯菌的分离情况及耐药性。结果分离的798株肺炎克雷伯菌主要来源于痰液489株(61.28%)及咽拭子137株(17.17%);产超广谱β-内酰胺酶肺炎克雷伯菌的检出率为37.47%;肺炎克雷伯菌对氨苄西林耐药率>90%,对磺胺二甲异恶唑耐药率>50%,对头孢哌酮/舒巴坦、头孢曲松、头孢吡肟等的耐药性有明显增加趋势。结论肺炎克雷伯菌的耐药率逐年增高,临床应加强对病原菌的分布及耐药性检测,以降低细菌的耐药性及医院的感染率。更多还原

【Abstract】 Objective To investigate the distribution and drug resistance of Klebsiella pneumonia causing noscomial infections so as to provide treatment recommendation for clinicians.Methods The various species were isolated,and the isolation and drug resistance of klebsiella pneumonia were retrospectively analyzed.Results 798 Klebsiella pneumonia strains were isolated,in which 489 from sputum(61.28%),137 from pharyngeal swab(17.17%).The detection rate of ESBLs-producing Klebsiella pneumonia was 37.47%.The drug resistance rate of Klebsiella pneumonia to ampicillin were higher than 90%,to sulfadimethisoxazol were more than 50%,and to cefoperazone-sulbactam,cefatriaxone and cefepime were increased significantly.Conclusions The antibiotic resistance rates of Klebsiella pneumoniaare rising.The detection of the distribution and drug resistance should be strengthen so as to reduce the incidence of drug resistance and noscomial infections.更多还原