【摘要】 目的:研究三白草Saururus chinensis抗尼古丁戒断症状有效部位中木脂素类化学成分。方法:采用各种柱色谱方法分离纯化,通过理化常数测定和光谱分析鉴定木脂素类化合物的结构。结果:从三白草抗戒断症状有效部位中分离鉴定得到13个化合物,分别为三白脂酮(1),三白脂酮A(2),1’-表三白脂酮(3),里卡灵B(4),里卡灵A(5),5-甲氧基-里卡灵A(6),三白脂素(7),5,5’-二甲氧基-三白脂素(8),nectandrin B(9),5,5’-dimethoxy-nectandrin B(10),3’,4’-methylenedioxy-3,4,5,5’-tetramethoxy-7,7’-epoxylignan(11),3’,4’-methylenedioxy-3,4,5-trimethoxy-7,7’-epoxylignan(12),machilin D(13)。结论:化合物6,8,10~12为首次从该植物中分离得到。更多还原

【Abstract】 Objective: To investigate into lignans of active components of Saururus chinensis anti-nicotine withdrawal symptoms.Method: Various column chromatography were used in the isolation and purification,and physiochemical constant determination and spectral analysis were adopted to determine the chemical structures of lignans.Result: Thirteen chemical compounds were isolated from the active of anti-withdrawal symptoms,sauchinone(1),sauchinone A(2),1’-epi-sauchinone(3),licarin B(4),licarin A(5),5-methoxy-licarin A(6),saucernetin(7),5,5’-dimethoxy-saucernetin(8),nectandrin B(9),5,5’-dimethoxy-nectandrin B(10),3’,4’-methylenedioxy-3,4,5,5’-tetramethoxy-7,7’-epoxylignan(11),3’,4’-methylenedioxy-3,4,5-trimethoxy-7,7’-epoxylignan(12),machilin D(13).Conclusion: Compounds 6,8,10-12 were first isolated from this plant.更多还原