【摘要】 目的分析80例抑郁症住院患者医院感染的临床特征,为临床防治提供指导和依据。方法回顾性分析80例抑郁症住院患者医院感染的临床资料。结果感染部位主要集中于下呼吸道、上呼吸道和胃肠道,分别占47.50%、26.25%和22.50%;共分离出84株病原菌,革兰阴性菌62株占73.81%、革兰阳性菌19株占22.62%和真菌3株占3.57%;前4位病原菌为大肠埃希菌、铜绿假单胞菌、金黄色葡萄球菌和肺炎克雷伯菌,分别占26.19%、20.24%、19.05%和16.67%;单纯西药组HAMD评分由治疗前的(23.4±3.2)分降为(10.6±4.8)分,而联合中药治疗组HAMD评分由治疗前的(23.7±3.0)分降至(6.8±3.3)分,两组治疗前后比较差异均有统计学意义(P<0.05);但治疗后两组比较,联合中药治疗组其HAMD评分明显降低,差异有统计学意义(P<0.05)。结论抑郁症住院患者的感染部位主要为呼吸道和消化道,且以革兰阴性菌为主,应针对上述因素做好防治工作。更多还原

【Abstract】 OBJECTIVE To analyze the clinical features of nosocomical infections in 80 inpatients with depression so as to guide the clinical prevention and treatment.METHODS The clinical data of 80 hospitalized depression patients with nosocomial infections were retrospectively reviewed.RESULTS The lower respiratory tract(47.50%),upper respiratory tract(26.25%),and gastrointestinal tract(22.50%)were the predominant infection sites.A total of 83 strains of pathogens were isolated,including 61 strains(73.81%)of gram-negative bacteria,19 strains(22.62%)of gram-positive bacteria,and 3 strains(3.57%)of fungi.Escherichia coli(26.19%),Pseudomonas aeruginosa(20.24%),Staphylococcus aureus(19.05%)and Klebsiella pneumoniae(16.67%) ranked the top four species of pathogens.The HAMD score in the single western medicine group dropped from(23.4±3.2)points to(10.6±4.8) points,while in the joint group the HAMD score dropped from(23.7±3.0)points to(6.8±3.3)points,the difference between the two groups before and after the treatment was statistically significant(P<0.05);after the treatment the HAMD score of the joint group was significantly lower than that of the single western medicine group,the difference was statistically significant(P<0.05).CONCLUSION The respiratory tract and the gastrointestinal tract are the main infection sites of the hospitalized depression patients,the gram-negative bacteria are the predominant pathogens.It is necessary to take effective prevention measures aiming at the factors discussed above.更多还原