【摘要】 目的探讨老年人社会经济因素与髋骨骨折的关系。方法采用1∶1配对的病例对照研究方法,收集2009年6月-2012年6月在广东省4所医院就诊的581名55～80岁新发髋骨骨折患者作为病例,同期招募性别、年龄(+/-3岁)匹配的广州市社区居民或非骨科相关疾病的病人作为对照。通过面对面访问调查其人口学特征及社会经济学情况。结果单因素条件logistic回归分析显示,已婚、文化程度高、职业体力活动低、收入和社会地位高、城镇居民及近5年经济状况好可降低髋骨骨折风险。在年龄、家族史及社会经济因素间相互校正后,婚姻状况、当前家庭人均收入及近5年经济状况的影响仍具有统计学意义。已婚者髋骨骨折风险是未婚、离异或丧偶者的0.44(95%CI:0.29～0.64)倍;家庭月收入最高组是最低组的0.26(95%CI:0.09～0.77)倍;近5年经济状况较好者风险是较差者的0.32(0.15～0.70)倍。分层和交互作用分析发现,近5年经济状况的影响在男性中更为明显(交互作用P=0.053)。结论社会经济状况较差及无配偶易增加髋骨骨折风险。更多还原

【Abstract】 Objective To investigate the relationship between demographic and socioeconomic factors and hip fractures.Methods 1∶1 matched case-control method was adopted.A total of 581 patients aging from 55 to 80 years old,who had new hip fractures and came to the 4 hospitals in Guangdong Province from June 2009 to June 2012,were enrolled in this study.At the same time,citizens in Guangzhou or patients without bone diseases,matched by gender and age(±3 years),were recruited as controls.Demographic characteristic and socioeconomic status were collected through face-to-face interview.Results Univariate logistic regression analysis showed significantly lower risks of hip fractures in subjects being married,with high level of education,household income,social status,and economic status within 5 years,and lower level of occupational physical activity.After adjustment for potential confounders(age,family history,and socioeconomic factors),the effect of the risks of hip fractures remained significant with marital status,household income,and economic status within 5 years.The risk of hip fractures was 0.44(95% CI: 0.29-0.64) folds in subjects being married compared with those in divorced,widowed,or unmarried ones.The risk in subjects with the highest household income was 0.26(95%CI: 0.09-0.77) times compared with that in subjects with the lowest household income.And the risk in those with good economic status within 5 years was 0.32(95% CI: 0.15-0.70) times compared with that in those with poor ones.Stratified and interaction analysis showed that the effect of economic status was more significant in the male than that in the female(P-interaction=0.053).Conclusion The risk of hip fractures increases in subjects with poor socioeconomic status or unmarried.更多还原