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棕榈花蕾水提物对雌兔激素水平的影响

Effects of aqueous extract of Trachycarpus fortunei on hormone level in female rabbits

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【作者】 齐汝霞张鹏姚晓红王传功李卫平

【Author】 QI Ru-xia 1, 2 , ZHANG Peng 2 , YAO Xiao-hong 3 , WANG Chuan-gong 2 , LI Wei-ping 1 1. Anhui Medical University, Hefei 230032 China 2. Jining Mdical University, Jining 272067 China 3. The First people’s Hospital of Jining, 272000 China

【机构】 安徽医科大学基础学院济宁医学院基础学院济宁第一人民医院

【摘要】 目的通过棕榈花蕾水提物对雌性家兔体内激素水平的影响,进一步探讨其抗生育作用机制。方法给健康雌性未孕家兔ip不同剂量的棕榈花蕾水提物,每天1次,连续9d。给药后分别从耳动脉取血,测定血清中的FT3、FT4、雌二醇、孕酮。结果与生理盐水组相比,棕榈花蕾水提物高剂量组明显降低家兔血清中FT3水平、升高孕酮含量,而各剂量组对FT4和雌二醇含量无明显影响。结论棕榈花蕾水提物能降低家兔血清中FT3水平,并升高孕酮含量。

【Abstract】 Objective To explore antifertility effects by the influence of Trachycarpus fortunei on hormone level in female rabbits. Methods To test the level of estradiol, progesterone and thyroid hormone by Elecsys 2010 after intraperitoneal injection of palm buds. Results FT3 was reduced and progesterone was increased obviously by high dose of AEPB. Three doses of AEPB have no effects on FT4 and estradiol. Conclusion Aqueous extract of palm buds have the effects of reducing FT3 and increasing progesterone.

【关键词】 棕榈雌性家兔FT3FT4雌二醇孕酮
【Key words】 Trachycarpus fortuneiFT3FT4estradiolprogesterone
  • 【文献出处】 药物评价研究 ,Drug Evaluation Research , 编辑部邮箱 ,2013年04期
  • 【分类号】R285.5
  • 【下载频次】73
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