【摘要】 目的探讨老年肝硬化患者医院感染情况及其相关危险因素。方法选择某院自2010年6月～2011年12月收治的126例老年肝硬化患者,对其临床资料进行回顾性调查分析,将发生医院感染的28例患者作为感染组,未发生医院感染的98例患者作为正常组,分析肝硬化患者医院感染的危险因素。结果 (1)肝硬化患者医院感染发生率为22.22%,感染组的病死率与正常组比较,差异有统计学意义(P﹤0.05);(2)感染部位主要包括肠道感染、肺部感染、泌尿系统感染以及皮肤软组织感染等;(3)老年肝硬化患者医院内感染与性别无关,与住院时间≥30d、肝功能差、有并发症、接受侵入性操作有关(P﹤0.05)。结论老年肝硬化患者医院感染是多种危险因素共同作用的结果 ,因此,应尽量缩短患者住院时间,改善患者的肝功能,合理使用抗生素,减少肝硬化患者医院感染的发生率。更多还原

【Abstract】 OBJECTIVE To investigate the situation of nosocomial infection for elderly patients with cirrhosis and analysis of its risk factors.METHODS 126 elderly patients with cirrhosis from June 2010 to December 2011 were chosen as the research objects.The clinical data were investigated and analyzed retrospectively.28 patients with nosocomial infection were chosen as the infection group.98 patients without nosocomial infection were set as the normal group.The risk factors of nosocomial infection in patients with cirrhosis were analyzed.RESULTS (1)The hospital infection rate for patients with cirrhosis was 22.22%,of which the fatality rate had significant difference compared with the normal group(P﹤0.05);(2)The sites of infection included intestinal infection,lung infection,urinary tract infection and skin and soft tissue infection;(3)The hospital infection of elderly patients with cirrhosis was not related with sex,but with length of stay ≥ 30d,poor liver function,complications,and undergoing an invasive operation(P﹤0.05).CONCLUSION The hospital infections in elderly patients with cirrhosis are the result of a variety of risk factors,so we should shorten the hospitalization time as possible,improve the patient’s liver function,and take rational use of antibiotics to reduce the incidence of nosocomial infection in patients with cirrhosis.更多还原