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米氮平联合认知疗法对伴有躯体疼痛症状的抑郁症的临床研究
A control study of mirtazapine combined with cognitive therapy in the treatment of depression with somatoform disorders
【摘要】 目的:探讨米氮平联合认知疗法治疗伴有躯体疼痛症状的抑郁症的临床疗效。方法:将60例伴躯体疼痛障碍的抑郁症患者随机分为两组各30例,分别给予单用米氮平及米氮平联合认知疗法治疗8周,于治疗前及治疗后第2、4、8周末采用汉密尔顿抑郁量表(HAMD)评定疗效。结果:治疗前两组汉密尔顿抑郁量表评分差异无显著性(P>0.05),治疗后第2、4、8周末两组汉密尔顿抑郁量表评分及研究用疼痛量表评分均较治疗前显著下降。结论:米氮平联合认知疗法治疗伴有躯体疼痛症状的抑郁症效果优于单用米氮平治疗组。
【Abstract】 objective: to assess the clinical efficacy of cognitive therapy combined with clomipramine in somatoform disorders.Methods: Sixty patients meeting diagnostic for depression with somatization disorder were randomly divided into two equal groups,trial group and control group.Patients of both groups were treated with clomipramine for 8 weeks,treatment group was also received cognitive therapy for 8 weeks.The treatment efficacy and HAMD values were observed before and after therapy.Results:At the end of the 8th week,incidences of each systemsymptom lowered more significantly and scores of HAMD or M0SPM did very more(P<0.01)compared with pretreatment.Conclusion: In the treatment of depression with somatization disorder,cognitive therapy and clomipramine has more effect than using clomipramine only.
【Key words】 mirtazapine; cognitive therapy; depression; somatoform disorders; HAMD;
- 【文献出处】 天津药学 ,Tianjin Pharmacy , 编辑部邮箱 ,2013年01期
- 【分类号】R749.4
- 【被引频次】3
- 【下载频次】82