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缺血性脑卒中后症状性癫痫临床特点分析

Clinical Features of Symptomatic Epilepsy after Ischemic Stroke

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【作者】 高筱雅陈晖郭曦华周月玲王慧杰

【Author】 GAO Xiao-ya;CHEN Hui;GUO Xi-hua;ZHOU Yue-ling;WANG Hui-jie;Zhujiang Hospital Department of Neurology of Southern Medical University;Three nine Brain Hospital of Guangdong;Zhujiang Hospital out-patient department of Southern Medical University;Tianjin People’s Liberation Army General Logistics Department,retired cadres;

【机构】 南方医科大学珠江医院神经内科广东三九脑科医院南方医科大学珠江医院门诊部中国人民解放军总后勤部天津第一干休所

【摘要】 目的:探讨缺血性卒中后继发癫痫的影响因素及其临床特点。方法:对我科2009年2月至2011年2月缺血性脑卒中467例进行回顾性分析,根据其有无症状性癫痫发作分为观察组和对照组,分析其影响因素、发生时间、类型及复发情况。结果:病灶累及皮质、SSS评分是脑卒中继发癫痫的显著影响因子。对早发性和晚发性癫痫复发情况比较,提示晚发性癫痫更容易复发。结论:缺血性脑卒中后如SSS评分较低、病灶累及皮质的患者应注意其继发癫痫的可能。早发性癫痫往往随着脑卒中病情的好转而得到控制,复发率低;晚发性癫痫复发率高,必要时需进行长期抗癫痫治疗。

【Abstract】 Objective:To explore the influencing factors and clinical features of epilepsy after ischemic stroke.Methods:467cases of ischemic stroke in our department from February 2009 to February 2011 were retrospectively analyzed,and were divided into observation group and control group according to their asymptomatic seizures.And their influencing factors,time of occurrence,type and recurrence were analyzed.Results:The lesions involving the cortex,the SSS scores were significant predictors of stroke for epilepsy.Compared with the recurrence of early-onset with late-onset epilepsy,late-onset epilepsy were more likely to relapse.Conclusion:After ischemic stroke,the patients with low SSS scores and the cortex lesions should be paid attention to secondary epilepsy.Early-onset epilepsy was often under control with the improvement of the condition of stroke,and the recurrence rate was low.However,when the recurrence rate of late-onset epilepsy was much higher,these patients usually needed long-term antiepileptic treatment if necessary.

【基金】 广东省医学科研基金项目(B2007106)
  • 【文献出处】 现代生物医学进展 ,Progress in Modern Biomedicine , 编辑部邮箱 ,2013年29期
  • 【分类号】R743
  • 【被引频次】1
  • 【下载频次】81
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