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高压氧在治疗抑郁症中的应用研究

The applied research about hyperbaric oxygen therapy on patients with depression.

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【作者】 郑晓秋; 向汉周; 王利; 陈代进;

【Author】 ZHENG Xiao-qiu;XIANGHan-zhou;WANG Li;The No. 2 People’s Hospital of Yibin;

【机构】 宜宾市第二人民医院高压氧科;

【摘要】 目的探讨高压氧治疗(HBOT)抑郁症的临床疗效。方法随机将84例符合抑郁症诊断的患者分为三组。A组:28例,单纯高压氧治疗;B组:30例,高压氧联合抗抑郁药物(帕罗西汀)治疗;C组:26例,单纯抗抑郁药物(帕罗西汀)治疗;结果经过4周的治疗,A组的有效率89.29%,治愈率57.14%;B有效率96.67%,治愈率83.33%;C组的有效率92.30%,治愈率61.53%。三组比较,P<0.05。结论高压氧和抗抑郁药物联合治疗抑郁症治愈率最高。单纯高压氧治疗抑郁症是有效的,且不良反应小,值得临床重视。

【Abstract】 Objective To observe the effect of hyperbaric oxygen therapy on patients with depression.Methods 84 patients with depression were randomly divided into three groups.A group(n = 28) treated with hyperbaric oxygen therapy purely;B group(n = 30) treated with hyperbaric oxygen therapy combined with antidepressant drugs(paroxetine);C group(n = 26) treated with antidepressant drugs(paroxetine) purely.Results After 4 weeks,the effective rate and recovery rate were 89.29% and 57.14% in A group,96.67% and 83.33% in B group,92.30% and 61.53% in C group,P<0.05.Conclusion The recovery rate of hyperbaric oxygen therapy combined with antidepressant drugs was the highest.Pure hyperbaric oxygen therapy was effective,with low adverse reaction.It would be worthy of clinical attention.

【关键词】 高压氧; 抑郁症; 帕罗西汀;
【Key words】 hyperbaric oxygen; depression; paroxetine;
【基金】 宜宾市卫生局立项科研[编号:(2010)277号]
  • 【文献出处】 四川医学 ,Sichuan Medical Journal , 编辑部邮箱 ,2013年08期
  • 【分类号】R749.4
  • 【被引频次】8
  • 【下载频次】53
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