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葛根素注射液联合鼠神经生长因子治疗视神经挫伤

Puerarin Combined with Mouse Nerve Growth Factor (mNGF) Treatment of Optic Nerve Contusion

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【作者】 勾晓梅李雪丽马新立周丽霞

【Author】 GOU Xiaomei;LI Xueli;MA Xinli;Harbin 242 Hospital;

【机构】 中航工业哈尔滨242医院眼科

【摘要】 目的:探讨葛根素注射液联合鼠神经生长因子(mNGF)治疗视神经挫伤的临床疗效。方法:70例(70只眼)视神经挫伤的住院患者随机数字法分为2组,治疗组35例(35只眼)采用葛根素注射液联合鼠神经生长因子治疗,同时应用激素治疗;对照组35例(35只眼)除不用葛根素外其他治疗不变。治疗21天后根据患者视力、VEP观察治疗前后的视神经挫伤变化情况评定临床疗效。结果:治疗组的总有效率为88.57%,高于对照组的65.71%,治疗后两组总有效率比较差异有统计学意义(P<0.05),治疗组疗效明显优于对照组。结论:葛根素注射液联合鼠神经生长因子治疗视神经挫伤安全、有效,值得临床推广应用。

【Abstract】 Objective: To investigate Puerarin combined with mouse nerve growth factor( mNGF) in significance in the treatment of Optic Nerve Contusion. Methods: 70cases( 70eyes) with Optic Nerve Contusion patients randomly divided into 2 groups,treatment group of 35 eyes in Puerarin combined with mouse nerve growth factor,control group of 35eyes of the same of treatment group therapy except treatment of Puerarin. Treatment after 21 days,according to the vision, VEP observation before and after treatment in patients with Optic Nerve Contusion changes in evaluation of clinical effect. Results: The total effectiveness of the treatment group was 88. 57%,control group was 65. 71%,there were statistically significant differences between the two groups( P < 0. 05). Conclusions: Puerarin injection combined with nerve growth factor in the treatment of optic nerve contusion to safe,effective,and clinical application.

  • 【文献出处】 航空航天医学杂志 ,Journal of Aerospace Medicine , 编辑部邮箱 ,2013年11期
  • 【分类号】R774.6
  • 【被引频次】2
  • 【下载频次】48
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