【摘要】 目的探讨患急性腹泻病的婴幼儿血锌水平变化及在常规治疗的基础上辅以补锌治疗的疗效。方法自2012年9月至2012年12月,分别测定了276例1个月～2岁患急性腹泻病婴幼儿和221例同年龄段健康婴幼儿的血锌水平;将276例急性腹泻病患儿随机分为两组,对照组122例,予以补液、肠黏膜保护剂、微生态制剂等常规治疗;治疗组154例在常规治疗的基础上,加用葡萄糖酸锌,比较两组的疗效。结果急性腹泻病患儿血锌水平明显低于对照组,差异有统计学意义(P<0.05和0.01);补锌治疗组总有效率为90.9%,高于对照组的80.3%,两组差异有统计学意义(P<0.05)。结论急性腹泻病婴幼儿血锌水平降低,在常规治疗的基础上佐以补锌治疗,可显著提高疗效。更多还原

【Abstract】 Objective To observe the serum zinc levels of infants with acute diarrhea and the efficacy of zinc supplementation treatment based on conventional therapy.Methods The serum zinc levels of 276 cases of infants with diarrhea and 221 cases of healthy infants,aged from 1 month to 2 years old,were detected respectively from September 2012 to December 2012.The infants with acute diarrhea were randomly divided into treatment group(154 cases) and control group(122 cases).Both groups received routine therapy.In addition,zinc gluconate was given to patients in the treatment group.Total effective rate was compared between the two groups.Results The serum zinc levels of infants with acute diarrhea were significantly lower than those of normal infants(P<0.05 and P<0.01).The total effective rate was significant higher in zinc supplementation treatment group than that in control group(90.9% vs.80.3%,P<0.05).Conclusion The serum zinc levels of infants with acute diarrhea are decreased.In addition to the conventional therapy for diarrhea,zinc treatment has better effect on enhancing curative effect of acute diarrhea.更多还原