【摘要】 目的了解克拉玛依市细菌性腹泻病病原学特点及流行病学特征,为细菌性腹泻病的防治提供理论依据。方法采集克拉玛依市第一人民医院门急诊腹泻病患者肛拭子,常规增菌、分离、纯化,根据国标应用生化鉴定法鉴定病原菌。结果该市112例腹泻病患者,致病菌检出29例,阳性检出率为25.89%;铜绿假单胞菌检出9例,检出率为8.04%。5岁以下婴幼儿为细菌性腹泻病高发人群。8月份为腹泻病高发期。致病菌构成中,铜绿假单胞菌占首位(31.03%),其次为沙门菌(24.14%)和志贺菌(24.14%)。沙门菌亚型主要以肠炎沙门菌和鼠伤寒沙门菌为主;而志贺菌只检测到福氏(B群)这一个亚型,痢疾(A群)、鲍氏(C群)以及宋内(D群)亚型均未检出,福氏志贺氏2a为优势菌株。结论该市细菌性腹泻病主要以婴幼儿高发,病原菌主要为铜绿假胞菌、沙门菌、志贺菌。铜绿假单胞菌引起的腹泻病应引起重视,避免滥用抗生素。更多还原

【Abstract】 [Objective]To understand the pathogenic feature and epidemiological characteristics of bacterial diarrhea in Karamay,provide the theoretical basis for prevention and control of bacterial diarrhea.[Methods]The anus swab samples were collected from diarrhea patients in Outpatient and Emergency Department of Karamay First People’s Hospital.After conventional enrichment,separation and purification,the pathogens were identified by biochemical identification according to national standards.[Results]Among 112 diarrhea patients,pathogenic bacteria were found in 29 cases with the positive rate of 25.89%,and Pseudomonas aeruginosa was found in 9 cases with the detection rate of 8.04%.Children under 5 years old had the highest incidence rate of bacterial diarrhea,and the peak reason was August.In pathogenic bacteria,Pseudomonas aeruginosa ranked at the first place(31.03%),followed by Salmonella(24.14%) and Shigella spp(24.14%).The subtypes of Salmonella mainly included Salmonella enteritidis and Salmonella typhimurium.Among subtypes of Shigella spp,only Shigellae flexneri(group B) was detected,while shigella dysenteriae(group A),Shigella boydii(group C) and Shigella sonnei(group D) were not found,and Shigella flexneri 2a was the dominant strain.[Conclusion]The incidence rate of bacterial diarrhea is higher among children in Karamay,and the main pathogenic bacteria include Pseudomonas aeruginosa,Salmonella and Shigella spp.It is necessary to pay attention to the diarrhea caused Pseudomonas aeruginosa,and control abuse of antibiotics.更多还原