【摘要】 植物细胞程序性死亡(PCD)在植物生长发育和逆境适应中发挥重要作用。半胱氨酸蛋白酶(caspase)调控动物PCD的启动、执行及信号转导。通过人工合成底物、动物caspase抑制剂等方法已证实在植物中存在类caspase,可分为metacaspases、VPEs(vacuolar processing enzymes)和saspases等。本文综述了植物类caspase的种类、结构、定位、功能及其调控PCD的研究进展,提出植物PCD中类caspase作用的调控途径,为深入研究植物PCD提供参考。更多还原

【Abstract】 Programmed cell death(PCD) plays an important role in the development and adaptation of plants under different environmental stresses.Cysteine-aspartic acid proteases(caspase) are responsible for initiating,executing and signal transduction of animal PCD.The existence of caspase-like proteases has been also demonstrated experimentally in plants by the applications of artificial synthesized substrates and inhibitors of caspase.Caspase-like proteases can be divided into three classes including metacaspases,vacuolar processing enzymes(VPEs) and saspases.In the paper,the progresses of the types,structures,locations,functions of caspase-like proteases and their regulatory roles in plant PCD are reviewed.Subsequently,a regulatory pathway of caspase-like proteases in plant PCD is also suggested.It can support a new insight into further study of caspase-like proteases and their effects in plant PCD.更多还原