【摘要】 目的观察中西医结合治疗幼儿手足口病的疗效。方法将本院收治的123例手足口病患儿随机分为两组,其中治疗组采用中西医结合治疗,中医治疗即口服中药,治疗原则为清热解毒、凉血祛湿。西医治疗即予以抗病毒、预防感染治疗及对症光疗,给予更昔洛韦5mg/kg静脉滴注,1次/d;有继发细菌感染症状者给予抗菌药物治疗;窄频中波紫外线(NUVB,311nm)照射治疗,隔日1次。对照组患儿单独给予更昔洛韦注射液(5mg/kg静脉滴注,1次/d)治疗。观察两组患儿的临床疗效,并详细记录其不良反应。结果治疗组和对照组患儿的总有效率分别为96.72%和83.87%,差异具有统计学意义(χ2=5.76,P<0.05)。两组患儿均未见严重的不良反应。结论中西医结合治疗幼儿手足口病安全且有效。更多还原

【Abstract】 Objective To observe the clinical efficacy of combination treatment of traditional Chinese medicine ( TCM) and Western medicine on infants with hand,foot and mouth disease. Methods Total of 123 infants with hand,foot and mouth disease were divided into treatment group ( 61 cases) and control group ( 62 cases) ,randomly. The cases in treatment group were given combination treatment of traditional Chinese medicine ( TCM ) and Western medicine. The therapeutic principle of TCM was heat-clearing and detoxification,blood cooling and dampness eliminating. Western treatments were antiviral therapy,infection prevention,preventing infection and expectant phototherapy with ganciclovir ( 5 mg / kg, injection intravenously,once a day) . Patients with bacterial infection were given prophylactic antibiotics and NB-UVB ( 311 nm) twice a day. Cases in control group were given ganciclovir ( 5 mg / kg,injection intravenously,once a day) only. The curative effects and adverse reactions were recorded. Results The total clinical efficiency on treatment group and control group were 96. 72% and 73. 33% ,respectively,with significant difference ( χ 2 = 5. 76,P < 0. 05) . There was no seriously adverse reaction between the two groups. Conclusions Combination of traditional Chinese medicine and Western medicine is safe and effective in the treatment on infants with hand,foot and mouth disease.更多还原