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小肠梗阻患者回肠系膜淋巴结细菌培养的初步研究

Preliminary Study of Bacterial Culture in Mesenteric Lymph Nodes of Patients with Small Bowel Obstruction

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【作者】 李世宽尚文周李元博彭新刚陆连芳张秋英

【Author】 LI Shi-kuan*,SHANG Wen-zhou*,LI Yuan-bo*,PENG Xin-gang*,LU Lian-fang*,ZHANG Qiu-ying*.* Department of Emergency General Surgery,Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,Shandong Province,China

【机构】 青岛大学医学院附属医院急诊普外科

【摘要】 目的研究小肠梗阻患者回肠系膜淋巴结细菌移位的发生情况及移位菌属。方法选取2009年7月至2011年7月期间我院急诊普外科收治的手术患者84例,分为研究组(n=42)与对照组(n=42),研究组为机械性小肠梗阻患者,对照组为腹部限期或择期手术不合并梗阻的患者。手术中无菌条件下切取回肠系膜淋巴结进行需氧菌和厌氧菌培养,比较2组细菌移位率及术后腹部感染发生率的差别,了解常见移位细菌种类。结果研究组患者细菌移位率明显高于对照组〔57.1%(24/42)比16.7%(7/42),χ2=14.775,P<0.01〕,大肠杆菌是最常见移位细菌(20)。急诊手术及年龄≥70岁与细菌移位发生有关(P<0.05)。发生细菌移位的患者其术后感染并发症发生率明显高于未发生细菌移位的患者〔29.0%(9/31)比3.8%(2/53),χ2=10.965,P<0.05〕。结论相对于择期手术,高龄、急诊小肠梗阻患者更易发生细菌移位。

【Abstract】 Objective To explore the bacterial translocation of mesenteric lymph nodes(MLNs) of the ileum and the spectrum of bacteria in patients with small bowel obstruction.MethodsTotal 84 patients were divided into study group(with small bowel obstruction) and control group(without small bowel obstruction).MLNs were obtained under sterile conditions intraoperatively,andwhich wereprocessed for cultureof aerobic and anaerobic organisms.The rate of bacterial translocation and postoperative infection were compared between two groups and the species of bacterial translocation was identified.ResultsThe bacterial translocation rate in the study group was higher than that in the control group(57.1%(24/42) versus 16.7%(7/42),χ2=14.775,P<0.01).Escherichia coil was the most commonly bacteria(20).Emergency surgery and age over 70 years were associated with bacterial translocation(P<0.05).Postoperative infection complications rate in the bacterial translocation patients was higher than that in the patients without bacterial translocation(29.0%(9/31) versus 3.8%(2/53),χ2=10.965,P<0.05).ConclusionsBacterial translocation to MLNs occurres more frequently in patients with small bowel obstruction,non-elective surgery,and elderly.

【基金】 黎介寿院士肠道屏障研究专项基金(项目编号:LJS_2009016)~~
  • 【文献出处】 中国普外基础与临床杂志 ,Chinese Journal of Bases and Clinics in General Surgery , 编辑部邮箱 ,2012年08期
  • 【分类号】R656.1
  • 【被引频次】3
  • 【下载频次】71
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