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舒肝解郁胶囊与帕罗西汀治疗抑郁症的对照研究

A comparative study of Shugan-jieyu capsule and Paroxetine in the treatment of depression

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【作者】 陶用富周豪龙吟张平范利芳

【Author】 TAO Yong-fu,ZHOU Hao,LONG Yin,et al(The mental health center of Mianyang,Sichuan 621000,China)

【机构】 四川省绵阳市精神卫生中心

【摘要】 目的:了解舒肝解郁胶囊对轻中度抑郁症的治疗效果及不良反应。方法:将符合CCMD-3轻中度抑郁症诊断标准的60例患者随机分为舒肝解郁组(30例)和帕罗西汀组(30例),分别在治疗前以及治疗后的第l、2、4、6周采用汉密尔顿抑郁量表(HAMD)评定疗效,采用副反应量表(TESS)评定不良反应。结果:舒肝解郁胶囊和帕罗西汀对于轻中度抑郁症均有显著疗效,2组间疗效无显著差异(P>0.05)。舒肝解郁组的不良反应明显小于帕罗西汀组(P<0.05)。结论:舒肝解郁胶囊治疗轻中度抑郁症安全有效,不良反应小。

【Abstract】 Objective:To evaluate the therapeutic effect and side effects of Shugan-jieyu capsule for treating the patients with depression.Methods:A total of 60 patients meeting the criteria of CCMD-3 for mild to moderate depression were randomly assigned to Shugan-jieyu capsule group(n=30) or Paroxetine group(n=30) for 6 weeks before and after treatments of 1,2,4,6 weeks.The efficacy and side effects were assessed with HAMD and TESS.Results: Both Shugan-jieyu capsule group and Paroxetine group showed significant improvement after treatment,while there was no significant difference between two groups.Shugan-jieyu capsule group had significantly less side effects than Paroxetine group.Conclusions: Shugan-jieyu capsule is safe and effective with slight side effects for treating patients with depression.

【关键词】 抑郁症舒肝解郁胶囊帕罗西汀
【Key words】 DepressionShugan-jieyu capsuleParoxetine
  • 【文献出处】 中国民康医学 ,Medical Journal of Chinese People’s Health , 编辑部邮箱 ,2012年19期
  • 【分类号】R749.41
  • 【被引频次】8
  • 【下载频次】95
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