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山东省2例输入性卵形疟病例报告

Two cases report of the imported ovale malaria in Shandong Province

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【作者】 肖婷魏艳彬刘凡李瑾黄炳成王用斌张本光尹昆孔庆安于振华李继民李登俊马巧荣付婷霞魏庆宽

【Author】 XIAO Ting,WEI Yan-bin,LIU Fan,et al(Shandong Academy of Medical Sciences,Shandong Institute of Parasitic Diseases,Jining,Shandong 272033,China)

【机构】 山东省医学科学院,山东省寄生虫病防治研究所

【摘要】 本文报告了2例国外输入卵形疟病例。两患者均为非洲几内亚务工返乡人员,回国后数月因发热、乏力而就医。入院血膜镜检见多期卵形疟疟原虫,环状体较粗大,大滋养体期、配子体期颗粒较粗;受染红细胞明显变形,呈多种不规则形状,具备卵形疟原虫特点。PCR基因产物约800bp,与卵形疟相符。对两患者应用蒿甲醚肌注和伯氨喹口服规范治疗,分别于7d、10d痊愈出院。

【Abstract】 This paper reported two ovale malaria cases who were imported from abroad.They both had worked in Equatorial Guinea,and they had received our medical treatment due to the fatigued fever after they returned to China few months later.Many stages of ovale malaria protozoa,thick ring forms,thick granulas in big trophozoite stage and gametophyte stage were found in blood test.The infected RBC were obviously disfigured,showed irregular shape,and the PCR results of gene diagnosis in two cases were 800 bp fragment size,all being ovals malaria characteristics.The patients received standard treatment with artemetheri intramuscularly and Primaquine orally,and finally they both were cured and discharged after seven and ten days respectively.

【关键词】 卵形疟输入性病例报告山东省
【Key words】 Ovale malariaimportedcase reportShandong Province
【基金】 中国全球基金疟疾项目实施性研究专项基金(No.201201055);山东省自然科学基金项目(No.ZR2011HL061)
  • 【文献出处】 中国病原生物学杂志 ,Journal of Pathogen Biology , 编辑部邮箱 ,2012年06期
  • 【分类号】R531.3
  • 【被引频次】31
  • 【下载频次】273
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