【摘要】 目的:更全面地阐明中药连翘的活性物质基础。方法:利用多种色谱方法分离连翘Forsythia suspensa果实的化学成分,并通过ESI-MS/MS及1D-和2D-NMR等波谱方法鉴定出24种化合物,它们的结构类型分别属于木脂素、黄酮、环己乙醇衍生物、三萜和神经酰胺。结果和结论:发现化合物1～10为首次从中药连翘果实中分离得到的神经酰胺类化合物,其中1,2,4,5的结构为首次报道。更多还原

【Abstract】 Twenty-four compounds in the fruits of Forsythia suspensa were isolated and purified by column chromatography and preparative TLC.On the basis of comprehensive spectroscopic methods including IR,ESI-MS/MS,1D and 2D NMR,these compounds were identified as ten ceremides(1-10),six triterpenes(11-16),one steroids(17),three flavonoids(18-20),two C6-C2 alcohols(21-22)and two lignans(23-24).Compounds 1-10 were reported from F.suspense for the first time,among which 1,2,4 and 5 were new ones.更多还原