【摘要】 目的探讨T2DM患者尿微量白蛋白与颈动脉内膜中层厚度(IMT)的相关性。方法微量白蛋白尿组(MAU)60例、30名健康者(NC)和30例正常白蛋白尿组(NMAU)作对照,测定血糖、UAER、血压及血肌酐等。采用彩色多普勒超声观察双侧颈动脉内膜中层厚度。结果 NMAU组较NC组FPG、IMT、SBP明显升高(P<0.05);MAU组较NC组FPG、SBP、UAER、IMT也明显升高(P<0.05);MAU组较NMAU组IMT、UAER显著升高(P<0.01)。MAU组患者UAER与IMT呈显著正相关(P<0.05)。结论 MAU与颈动脉硬化密切相关,MAU可能为大血管及微血管病变的标志物。更多还原

【Abstract】 Objective To explore the relationship between microalbuminuria and carotid intima-media thickness in type 2 diabetic patients.Methods Sixty microalbuminuria patients(MAU,UAER20-200 μg/min),30 nonmicroalbuminuria patients(NMAU,UAER<20 μg/min) and 30 healthy people(NC) were selected in the reserch.The levels of glucose,UAER,blood-pressure and serum creatinine were measured.IMT of carotid arteries were determined with high-sensitive B-mode ultrasound.Results The levels of glucose,IMT,SBP were significantly increased in NMAU versus NC group(all P<0.05).The levels of glucose,SBP,UAER and IMT were increased significantly in MAU versus NC group(all P<0.05).The levels of IMT and UAER were increased in MAU than in NMAU group(P<0.05).UAER was negatively correlated with IMT.Conclusions Microalbuminuria is negatively correlated with IMT.Microalbuminuria level is likely to be a marker of diabetes’ complications.更多还原